Cyanidioschyzon merolae      Atypical      ABC1

※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusEKPD IDGene IDGene Name
1
EKS-CYM-00021
CMN159C
2
EKS-CYM-00015
CMR400C
3
EKS-CYM-00020
CMT177C
4
EKS-CYM-00017
CMQ260C
5
EKS-CYM-00019
CMG161C
6
EKS-CYM-00016
CML057C
7
EKS-CYM-00018
CMA056C
8
EKS-CYM-00012
CMS164C
9
EKS-CYM-00014
CMG075C
10
EKS-CYM-00013
CMP122C
11
EKS-CYM-00011
CMB043C