※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-GAA-00157	ENSGACG00000003821	ADCK2
2		EKS-GAA-00152	ENSGACG00000020138	ADCK1
3		EKS-GAA-00155	ENSGACG00000008688	ADCK5
4		EKS-GAA-00156	ENSGACG00000011714	ADCK3 (2 of 2)
5		EKS-GAA-00153	ENSGACG00000013145	ADCK3 (1 of 2)
6		EKS-GAA-00154	ENSGACG00000005843	ADCK4