※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SOT-00554	PGSC0003DMG400005040	PGSC0003DMG400005040
2		EKS-SOT-00556	PGSC0003DMG400025664	PGSC0003DMG400025664
3		EKS-SOT-00555	PGSC0003DMG400025002	PGSC0003DMG400025002
4		EKS-SOT-00552	PGSC0003DMG404029448	PGSC0003DMG404029448
5		EKS-SOT-00557	PGSC0003DMG400024209	PGSC0003DMG400024209
6		EKS-SOT-00553	PGSC0003DMG400003549	PGSC0003DMG400003549
7		EKS-SOT-00558	PGSC0003DMG400022947	PGSC0003DMG400022947