※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SUS-00117	ENSSSCG00000010861	ADCK3
2		EKS-SUS-00118	ENSSSCG00000005907	ADCK5
3		EKS-SUS-00120	ENSSSCG00000026331	ADCK4
4		EKS-SUS-00119	ENSSSCG00000016496	ADCK2
5		EKS-SUS-00116	ENSSSCG00000002408	ADCK1