※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-TAR-00175	ENSTRUG00000013058	ADCK5
2		EKS-TAR-00172	ENSTRUG00000014182	ADCK3 (1 of 2)
3		EKS-TAR-00174	ENSTRUG00000006469	ADCK3 (2 of 2)
4		EKS-TAR-00173	ENSTRUG00000001653	ADCK4
5		EKS-TAR-00171	ENSTRUG00000000665	ADCK1
6		EKS-TAR-00176	ENSTRUG00000016512	ADCK2