※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-TEN-00168	ENSTNIG00000005807	ADCK2
2		EKS-TEN-00164	ENSTNIG00000014337	ADCK4
3		EKS-TEN-00167	ENSTNIG00000014028	ADCK5
4		EKS-TEN-00163	ENSTNIG00000010950	ADCK3 (1 of 2)
5		EKS-TEN-00165	ENSTNIG00000019321	ADCK3 (2 of 2)
6		EKS-TEN-00166	ENSTNIG00000003749	ADCK1