Gasterosteus aculeatus      CAMK      DCAMKL

※ DCAMKL family introduction

    DCAMKL, Doublecortin-like and CAM kinase-like protein, belong to CAMKL group. Three members have been found in human, DCAMKL1-3. DCAMKL1 may participate in calcium-signaling pathway and control the neuronal migration in the developing brain (1). DCAML2 has little Ca(2+)/CAM affinity compared with other CAMK proteins and may be involved in down regulation of CRE-dependent gene activation via phosphorylating CREB coactivator CRT/TORC2 (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation: DCLK1_HUMAN
3. UniProt Annotation: DCLK2_HUMAN


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusEKPD IDGene IDGene Name
1
EKS-GAA-00418
ENSGACG00000020560
DCLK1 (1 of 2); DCLK1 (2 of 2)
2
EKS-GAA-00419
ENSGACG00000011579
DCLK1 (1 of 2); DCLK1 (2 of 2)
3
EKS-GAA-00417
ENSGACG00000017187
DCLK2 (1 of 2)
4
EKS-GAA-00420
ENSGACG00000005594
DCLK3