Rattus norvegicus      CAMK      DCAMKL

※ DCAMKL family introduction

    DCAMKL, Doublecortin-like and CAM kinase-like protein, belong to CAMKL group. Three members have been found in human, DCAMKL1-3. DCAMKL1 may participate in calcium-signaling pathway and control the neuronal migration in the developing brain (1). DCAML2 has little Ca(2+)/CAM affinity compared with other CAMK proteins and may be involved in down regulation of CRE-dependent gene activation via phosphorylating CREB coactivator CRT/TORC2 (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation: DCLK1_HUMAN
3. UniProt Annotation: DCLK2_HUMAN


There are 3 genes.  Reviewed (2 or Unreviewed (1

No.StatusEKPD IDGene IDGene Name
1
EKS-RAN-00358
ENSRNOG00000016550
Dcamkl2, Dck2; Dclk2
2
EKS-RAN-00359
ENSRNOG00000033026
Dclk3
3
EKS-RAN-00357
ENSRNOG00000032922
Dclk1; Cpg16, Dcamkl1