Tetraodon nigroviridis      CAMK      DCAMKL

※ DCAMKL family introduction

    DCAMKL, Doublecortin-like and CAM kinase-like protein, belong to CAMKL group. Three members have been found in human, DCAMKL1-3. DCAMKL1 may participate in calcium-signaling pathway and control the neuronal migration in the developing brain (1). DCAML2 has little Ca(2+)/CAM affinity compared with other CAMK proteins and may be involved in down regulation of CRE-dependent gene activation via phosphorylating CREB coactivator CRT/TORC2 (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. UniProt Annotation: DCLK1_HUMAN
3. UniProt Annotation: DCLK2_HUMAN


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusEKPD IDGene IDGene Name
1
EKS-TEN-00438
ENSTNIG00000016267
DCLK1 (1 of 2); DCLK1 (2 of 2)
2
EKS-TEN-00440
ENSTNIG00000016978
DCLK3
3
EKS-TEN-00436
ENSTNIG00000017733
DCLK2 (1 of 2)
4
EKS-TEN-00437
ENSTNIG00000009924
DCLK1 (1 of 2); DCLK1 (2 of 2)
5
EKS-TEN-00439
ENSTNIG00000011249
DCLK2 (2 of 2)