※ CK1 family introduction

    CK1 (Casein kinase I) are characterized by its ser/thr protein kinase catalytic activity on phoshorylation of casein in vitro in a cycle AMP-independent manner. Six isoforms and CK1-like kinase have been identified in this family. Sequence analysis show that all members share a N-terminal conserved kinase catalytic domain and a variable C-terminal sequence. Several potential regulatory mechanisms for CK1s have been described, including activation via phosphorylation of PKA, 14-3-3 binding and autoinhibition. CK1s are involved in a variety of cellular processes via phosphorylation of a large range of substrates, for instance, stabilize AIB1 and increase Erα transcriptional activity, facilitate CK1α/FADD/CaM complex assembly for proper cell cycle progression, reduces DNA-binding activity of Dnmt1, blocks nuclear export and so on. (1)

Reference
1. Cheong, J.K. and Virshup, D.M. (2011) Casein kinase 1: Complexity in the family. Int J Biochem Cell Biol, 43, 465-469. PMID: 21145983

  Reviewed (0)  or Unreviewed (16) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ARL-00952	fgenesh2_kg.3__2550__AT3G23340.1	XM_002883378.1
2		EKS-ARL-00950	fgenesh2_kg.8__402__AT5G44100.1	XM_002863565.1
3		EKS-ARL-00959	fgenesh2_kg.7__1302__AT4G28880.1	XM_002869420.1
4		EKS-ARL-00956	fgenesh2_kg.8__487__AT5G43320.1	XM_002863618.1
5		EKS-ARL-00958	Al_scaffold_0006_3004	XM_002872369.1
6		EKS-ARL-00960	fgenesh2_kg.7__1304__AT4G28860.2	XM_002869421.1
7		EKS-ARL-00954	scaffold_303905.1	XM_002883942.1
8		EKS-ARL-00961	fgenesh2_kg.4__489__AT2G25760.1	XM_002880660.1
9		EKS-ARL-00962	scaffold_300387.1	XM_002884375.1
10		EKS-ARL-00963	Al_scaffold_0001_315	XM_002889438.1
11		EKS-ARL-00955	scaffold_703186.1	XM_002868245.1
12		EKS-ARL-00949	scaffold_802263.1	XM_002864445.1
13		EKS-ARL-00951	fgenesh2_kg.2__1538__AT1G72710.1	XM_002887402.1
14		EKS-ARL-00953	fgenesh2_kg.7__1343__AT4G28540.1	XM_002869449.1
15		EKS-ARL-00948	fgenesh2_kg.7__1637__AT4G26100.1	XM_002867534.1
16		EKS-ARL-00957	scaffold_100403.1	XM_002889459.1