※ CK1 family introduction

    CK1 (Casein kinase I) are characterized by its ser/thr protein kinase catalytic activity on phoshorylation of casein in vitro in a cycle AMP-independent manner. Six isoforms and CK1-like kinase have been identified in this family. Sequence analysis show that all members share a N-terminal conserved kinase catalytic domain and a variable C-terminal sequence. Several potential regulatory mechanisms for CK1s have been described, including activation via phosphorylation of PKA, 14-3-3 binding and autoinhibition. CK1s are involved in a variety of cellular processes via phosphorylation of a large range of substrates, for instance, stabilize AIB1 and increase Erα transcriptional activity, facilitate CK1α/FADD/CaM complex assembly for proper cell cycle progression, reduces DNA-binding activity of Dnmt1, blocks nuclear export and so on. (1)

Reference
1. Cheong, J.K. and Virshup, D.M. (2011) Casein kinase 1: Complexity in the family. Int J Biochem Cell Biol, 43, 465-469. PMID: 21145983

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-GLM-02238	GLYMA05G35680
2		EKS-GLM-02235	GLYMA20G35100
3		EKS-GLM-02251	GLYMA04G09080
4		EKS-GLM-02250	GLYMA08G21570
5		EKS-GLM-02239	GLYMA01G34780
6		EKS-GLM-02254	GLYMA15G18800
7		EKS-GLM-02245	GLYMA15G18741
8		EKS-GLM-02234	GLYMA15G18700
9		EKS-GLM-02230	GLYMA13G18690
10		EKS-GLM-02227	GLYMA17G06140
11		EKS-GLM-02233	GLYMA13G42380
12		EKS-GLM-02229	GLYMA10G04430
13		EKS-GLM-02242	GLYMA04G08800
14		EKS-GLM-02247	GLYMA18G53810
15		EKS-GLM-02244	GLYMA17G28694
16		EKS-GLM-02236	GLYMA19G34930
17		EKS-GLM-02237	GLYMA03G32170
18		EKS-GLM-02243	GLYMA06G08880
19		EKS-GLM-02228	GLYMA15G03000
20		EKS-GLM-02226	GLYMA13G16540
21		EKS-GLM-02240	GLYMA08G04000
22		EKS-GLM-02253	GLYMA03G24421
23		EKS-GLM-02241	GLYMA09G32640
24		EKS-GLM-02249	GLYMA07G01890
25		EKS-GLM-02246	GLYMA07G00970
26		EKS-GLM-02248	GLYMA08G47680
27		EKS-GLM-02231	GLYMA10G32490
28		EKS-GLM-02225	GLYMA08G20320
29		EKS-GLM-02232	GLYMA09G07490
30		EKS-GLM-02252	GLYMA16G04580