※ CK1 family introduction

    CK1 (Casein kinase I) are characterized by its ser/thr protein kinase catalytic activity on phoshorylation of casein in vitro in a cycle AMP-independent manner. Six isoforms and CK1-like kinase have been identified in this family. Sequence analysis show that all members share a N-terminal conserved kinase catalytic domain and a variable C-terminal sequence. Several potential regulatory mechanisms for CK1s have been described, including activation via phosphorylation of PKA, 14-3-3 binding and autoinhibition. CK1s are involved in a variety of cellular processes via phosphorylation of a large range of substrates, for instance, stabilize AIB1 and increase Erα transcriptional activity, facilitate CK1α/FADD/CaM complex assembly for proper cell cycle progression, reduces DNA-binding activity of Dnmt1, blocks nuclear export and so on. (1)

Reference
1. Cheong, J.K. and Virshup, D.M. (2011) Casein kinase 1: Complexity in the family. Int J Biochem Cell Biol, 43, 465-469. PMID: 21145983

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SOL-00987	Solyc06g062790.2	Solyc06g062790.2
2		EKS-SOL-00985	Solyc07g040720.2	Solyc07g040720.2
3		EKS-SOL-00993	Solyc08g066870.2	Solyc08g066870.2
4		EKS-SOL-00986	Solyc06g008320.2	Solyc06g008320.2
5		EKS-SOL-00998	Solyc09g090230.1	Solyc09g090230.1
6		EKS-SOL-00984	Solyc03g121820.2	Solyc03g121820.2
7		EKS-SOL-00990	Solyc06g053560.2	Solyc06g053560.2
8		EKS-SOL-00997	Solyc08g066410.1	Solyc08g066410.1
9		EKS-SOL-00989	Solyc06g083830.2	Solyc06g083830.2
10		EKS-SOL-00988	Solyc09g066440.2	Solyc09g066440.2
11		EKS-SOL-00996	Solyc01g006120.2	Solyc01g006120.2
12		EKS-SOL-00991	Solyc09g090250.2	Solyc09g090250.2
13		EKS-SOL-00995	Solyc12g095830.1	Solyc12g095830.1
14		EKS-SOL-00992	Solyc12g007280.1	Solyc12g007280.1
15		EKS-SOL-00994	Solyc11g070170.1	Solyc11g070170.1
16		EKS-SOL-00983	Solyc05g016410.2	Solyc05g016410.2