※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-BRD-01018	BRADI2G06490	BRADI2G06490
2		EKS-BRD-01019	BRADI2G38590	BRADI2G38590
3		EKS-BRD-01021	BRADI3G09067	BRADI3G09067
4		EKS-BRD-01015	BRADI2G11370	BRADI2G11370
5		EKS-BRD-01017	BRADI2G08890	BRADI2G08890
6		EKS-BRD-01014	BRADI1G02160	BRADI1G02160
7		EKS-BRD-01020	BRADI3G31480	BRADI3G31480
8		EKS-BRD-01016	BRADI2G32620	BRADI2G32620