Glycine max      CMGC      GSK

※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387


There are 23 genes.  Reviewed (0 or Unreviewed (23

No.StatusEKPD IDGene IDGene Name
1
EKS-GLM-00201
GLYMA05G29200
2
EKS-GLM-00182
GLYMA10G28530
GSK-3
3
EKS-GLM-00184
GLYMA20G22600
4
EKS-GLM-00195
GLYMA13G36570
5
EKS-GLM-00192
GLYMA15G09090
6
EKS-GLM-00187
GLYMA03G38850
7
EKS-GLM-00193
GLYMA03G01850
8
EKS-GLM-00186
GLYMA07G08320
9
EKS-GLM-00181
GLYMA18G45960
10
EKS-GLM-00202
GLYMA06G43620
11
EKS-GLM-00194
GLYMA12G15470
12
EKS-GLM-00196
GLYMA04G06760
13
EKS-GLM-00197
GLYMA06G42840
14
EKS-GLM-00191
GLYMA13G30060
15
EKS-GLM-00189
GLYMA12G28730
16
EKS-GLM-00190
GLYMA10G01280
17
EKS-GLM-00185
GLYMA19G41420
18
EKS-GLM-00200
GLYMA08G12370
19
EKS-GLM-00183
GLYMA16G00400
20
EKS-GLM-00180
GLYMA09G40150
21
EKS-GLM-00198
GLYMA06G06850
22
EKS-GLM-00188
GLYMA02G01220
23
EKS-GLM-00199
GLYMA12G33950