※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SOL-00916	Solyc10g037910.1	Solyc10g037910.1
2		EKS-SOL-00909	Solyc01g101000.2	Solyc01g101000.2
3		EKS-SOL-00915	Solyc03g006070.2	Solyc03g006070.2
4		EKS-SOL-00911	Solyc01g091620.2	Solyc01g091620.2
5		EKS-SOL-00914	Solyc02g072300.2	Solyc02g072300.2
6		EKS-SOL-00907	Solyc12g062870.1	Solyc12g062870.1
7		EKS-SOL-00912	Solyc05g051050.2	Solyc05g051050.2
8		EKS-SOL-00908	Solyc02g086670.2	Solyc02g086670.2
9		EKS-SOL-00917	Solyc06g082640.2	Solyc06g082640.2
10		EKS-SOL-00913	Solyc07g055200.2	Solyc07g055200.2
11		EKS-SOL-00910	Solyc01g103430.2	Solyc01g103430.2