※ GSK family introduction

    GSK (Glycogen synthase kinase 3) belong to CMGC family. Two isoforms have been identified in human genome, known as GSK3A and GSK3B. GSKs are highly conserved and have been found in nearly all eukaryote. Sequence analysis show that two genes display 85% sequence identity, and even higher in the catalytic domain (93%). Chromosomal mapping identified the cytological location of human GSK3A as 19q13.2, whereas human GSK3B maps to 3q13.3. Northern blot analysis shows that GSKs are expressed in different mammalian tissues. GSKs play an important role in a variety of cellular signaling pathways, including cellular proliferation, migration, inflammation and immue responses, glucose regulation and apoptosis (1).

Reference
3. Ali, A., Hoeflich, K.P. and Woodgett, J.R. (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev, 101, 2527-2540. PMID: 11749387

  Reviewed (0)  or Unreviewed (7) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SOB-01058	Sb03g009580	SB03G009580; Sb03g009580; SORBIDRAFT_03g009580
2		EKS-SOB-01056	Sb03g012070
3		EKS-SOB-01059	Sb03g002380	SORBIDRAFT_03g002380; SB03G002380; Sb03g002380
4		EKS-SOB-01055	Sb04g008580	SORBIDRAFT_04g008580; Sb04g008580; SB04G008580
5		EKS-SOB-01054	Sb01g001760	SB01G001760; SORBIDRAFT_01g001760; Sb01g001760
6		EKS-SOB-01057	Sb09g002710	Sb09g002710; SB09G002710; SORBIDRAFT_09g002710
7		EKS-SOB-01060	Sb01g031220	SB01G031220; Sb01g031220; SORBIDRAFT_01g031220