※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (13) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-MUP-00463	ENSMPUG00000008813	MAPK4
2		EKS-MUP-00458	ENSMPUG00000002272	MAPK11
3		EKS-MUP-00454	ENSMPUG00000002290	Mapk10
4		EKS-MUP-00461	ENSMPUG00000002323	Mapk12
5		EKS-MUP-00453	ENSMPUG00000004068	Mapk13
6		EKS-MUP-00452	ENSMPUG00000012636	MAPK3
7		EKS-MUP-00451	ENSMPUG00000003927	Mapk14
8		EKS-MUP-00462	ENSMPUG00000007628	Mapk6
9		EKS-MUP-00456	ENSMPUG00000003144	Mapk1
10		EKS-MUP-00457	ENSMPUG00000000046	Mapk7
11		EKS-MUP-00459	ENSMPUG00000000593	Mapk9
12		EKS-MUP-00460	ENSMPUG00000014360	NLK
13		EKS-MUP-00455	ENSMPUG00000009129	MAPK8