※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (12) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SEM-00989	SELMODRAFT_449503	SELMODRAFT_449503; MPK_1
2		EKS-SEM-00979	SELMODRAFT_449420	MPK4-2; MPK4-1; SELMODRAFT_449420, SELMODRAFT_449423
3		EKS-SEM-00978	SELMODRAFT_449429	MPK1; SELMODRAFT_449429
4		EKS-SEM-00983	SELMODRAFT_82767	SELMODRAFT_82767
5		EKS-SEM-00982	SELMODRAFT_232896	SELMODRAFT_232896
6		EKS-SEM-00985	SELMODRAFT_450114	SELMODRAFT_450114; MPK9-1
7		EKS-SEM-00981	SELMODRAFT_450113	SELMODRAFT_450112, SELMODRAFT_450113; MPK2-1; MPK2-2
8		EKS-SEM-00980	SELMODRAFT_450111	MPK1-2; SELMODRAFT_450111
9		EKS-SEM-00987	SELMODRAFT_450116	MPK9-2; SELMODRAFT_450116
10		EKS-SEM-00986	SELMODRAFT_450117	MPK16-1; SELMODRAFT_450117
11		EKS-SEM-00984	SELMODRAFT_86578	SELMODRAFT_86578; MPK_2
12		EKS-SEM-00988	SELMODRAFT_131428	SELMODRAFT_131428