※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200

  Reviewed (0)  or Unreviewed (6) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-GAA-00219	ENSGACG00000003832	SRPK2
2		EKS-GAA-00220	ENSGACG00000003742
3		EKS-GAA-00215	ENSGACG00000007667	SRPK1 (1 of 2); SRPK1 (2 of 2)
4		EKS-GAA-00217	ENSGACG00000012098
5		EKS-GAA-00218	ENSGACG00000008145	SRPK1 (1 of 2); SRPK1 (2 of 2)
6		EKS-GAA-00216	ENSGACG00000000600	SRPK3