※ SRPK family introduction

    SRPK (serine-arginine (SR) protein kinase) belong to CMGC family. Three members have been identified in human genome, which are known as SRPK1, SRPK2 and SRPK3. SRPKs are characterized by the ability to phosphorylate the serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. More than 100 proteins contain RS domains, indicating that SRPKs are involved in a variety of cellular functions, including regulation and function in mRNA maturation, regulation of chromatin binding to the nuclear envelope, regulation of chromatin reorganization during G2/M phase progression, regulation of cyclin transcription and involved in metabolic signaling (1).

Reference
1. Giannakouros, T., Nikolakaki, E., Mylonis, I. and Georgatsou, E. (2011) Serine-arginine protein kinases: a small protein kinase family with a large cellular presence. FEBS J, 278, 570-586. PMID: 21205200

  Reviewed (0)  or Unreviewed (6) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ORL-00214	ENSORLG00000001246
2		EKS-ORL-00211	ENSORLG00000020076	SRPK3
3		EKS-ORL-00212	ENSORLG00000016119	SRPK1 (2 of 2)
4		EKS-ORL-00213	ENSORLG00000014212
5		EKS-ORL-00209	ENSORLG00000002625	SRPK2
6		EKS-ORL-00210	ENSORLG00000006445	SRPK1 (1 of 2)