※ aDSP family introduction

    aDSP (Atypical DSP) family contains phosphatases which are poorly characterized, they are smaller than MKP family and lack specific MAP kinase motifs (1). Family member DUSP3 is invloved in down-regulating the ERK pathway and specifically dephosphorylates and inactivates ERK1 and ERK2 (2). DUSP11 show phosphatase activity towards RNA 5'-triphosphatase and may participate in nuclear mrna metabolism. The studies show that most of aDSP phosphatase have function unrelated to MAP kinases (3).

Reference
1. Alonso, A., Sasin, J., Bottini, N., Friedberg, I., Osterman, A., Godzik, A., Hunter, T., Dixon, J. and Mustelin, T. (2004) Protein tyrosine phosphatases in the human genome. Cell, 117, 699-711. PMID:15186772
2. Todd, J.L., Tanner, K.G. and Denu, J.M. (1999) Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathway. J Biol Chem, 274, 13271-13280. PMID: 10224087
3. Yuan, Y., Li, D.M. and Sun, H. (1998) PIR1, a novel phosphatase that exhibits high affinity to RNA . ribonucleoprotein complexes. J Biol Chem, 273, 20347-20353. PMID: 9685386

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EPS-ARL-00009	fgenesh2_kg.8__1567__AT5G56610.1	XM_002864425.1
2		EPS-ARL-00013	scaffold_600085.1	XM_002872971.1
3		EPS-ARL-00015	scaffold_602982.1	XM_002872264.1
4		EPS-ARL-00012	fgenesh2_kg.5__1574__AT3G52180.1	XM_002877801.1
5		EPS-ARL-00010	fgenesh1_pg.C_scaffold_3000057	XM_002882131.1
6		EPS-ARL-00008	scaffold_402179.1	XM_002881362.1
7		EPS-ARL-00006	fgenesh2_kg.6__2366__AT5G23720.1	XM_002872023.1
8		EPS-ARL-00011	fgenesh2_kg.3__923__AT3G09100.2	XM_002884667.1
9		EPS-ARL-00007	scaffold_100018.1	XM_002891981.1
10		EPS-ARL-00014	fgenesh2_kg.3__1136__AT3G10940.1	XM_002884777.1