※ Aur family introduction

    Aurora kinases are classified into "Other" group. Three members have been identified in human genome, AurA, AurB and AurC. Sequence analysis show that Aur kinases contain a conserved kinase catalytic domain flanked by N-terminal and C-terminal regulatory sequence. AurA gene is located within the chromosome locus 20q13, which is a frequently detected in human breast tumors, and AurA is essential for the proper progression through mitosis. AurB is a chromosome passenger involved in cytokinesis and chromosome architecture and AurC plays a role in spermatogenesis at the time when cells assemble the two meiotic spindles, AurC can also cooperates with AurB to regulate mitotic chromosome dynamics. AurA has been reported to be a good marker of tumor progression and prognosis, which can be applied on disease diagnosis and treatment (1).

Reference
1. Bolanos-Garcia, V.M. (2005) Aurora kinases. Int J Biochem Cell Biol, 37, 1572-1577. PMID: 15896667

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SOB-00617	Sb01g007100	SB01G007100; SORBIDRAFT_01g007100; Sb01g007100
2		EKS-SOB-00615	Sb04g026150	Sb04g026150; SORBIDRAFT_04g026150; SB04G026150
3		EKS-SOB-00616	Sb09g002100	SORBIDRAFT_09g002100; SB09G002100; Sb09g002100
4		EKS-SOB-00614	Sb03g003130	SB03G003130; Sb03g003130; SORBIDRAFT_03g003130