※ PP1 family introduction

    PP1 enzyme is composed of a catalytic subunit and a regulatory subunit(R subunit), and the catalytic domain is conserved among all eukaryotes, more than 100 regulatory subunit have been found to interact with C domain. Therefore, PP1 is a functional diversity protein phosphatases, which regulates a varieties of cellular processes through dephosphorylate different substrate. PP1 can promote the rational use of energy, especially when nutrients are abundant. PP1 plays a key role in the recovery from stress but promotes apoptosis when cells are damaged beyond repair. In addition, PP1 can regulate the cell cycle (1).

Reference
1. Ceulemans, H. and Bollen, M. (2004) Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev, 84, 1-39. PMID: 14715909

  Reviewed (0)  or Unreviewed (6) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EPS-SOT-00104	PGSC0003DMG400023403	PGSC0003DMG400023403
2		EPS-SOT-00106	PGSC0003DMG400016290	PGSC0003DMG400016290
3		EPS-SOT-00105	PGSC0003DMG400006739	PGSC0003DMG400006739
4		EPS-SOT-00107	PGSC0003DMG400030424	PGSC0003DMG400030424
5		EPS-SOT-00109	PGSC0003DMG402024761	PGSC0003DMG402024761
6		EPS-SOT-00108	PGSC0003DMG400017227	PGSC0003DMG400017227