Latimeria chalumnae      PPP      PP2B

※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusEKPD IDGene IDGene Name
1
EPS-LAC-00083
ENSLACG00000010549
PPP3CB
2
EPS-LAC-00080
ENSLACG00000001093
PPP3CA
3
EPS-LAC-00081
ENSLACG00000004597
4
EPS-LAC-00082
ENSLACG00000004479
PPP3CC