Canis familiaris      PTPLA      PTPLA

※ PTPLA family introduction

    PTPLA, Protein tyrosine phosphatase-like protein, contains protein tyrosine phosphatase-like proteins. Classical PTP is characterized by its signure motif CXXXXXR, however, the Arg to Pro(R/P) variation is found at active site in PTPLA. And PTPLA have been thought to play an important role in development, differentiation, and maintenance of a number of tissue types (1).

Reference
1. Uwanogho, D.A., Hardcastle, Z., Balogh, P., Mirza, G., Thornburg, K.L., Ragoussis, J. and Sharpe, P.T. (1999) Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene. Genomics, 62, 406-416. PMID: 10644438


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusEKPD IDGene IDGene Name
1
EPS-CAF-00129
ENSCAFG00000001652
PTPLAD2
2
EPS-CAF-00128
ENSCAFG00000017232
PTPLAD1
3
EPS-CAF-00126
ENSCAFG00000023975
Cfa.38724; PTPLA
4
EPS-CAF-00127
ENSCAFG00000012091
PTPLB