Gasterosteus aculeatus      PTPLA      PTPLA

※ PTPLA family introduction

    PTPLA, Protein tyrosine phosphatase-like protein, contains protein tyrosine phosphatase-like proteins. Classical PTP is characterized by its signure motif CXXXXXR, however, the Arg to Pro(R/P) variation is found at active site in PTPLA. And PTPLA have been thought to play an important role in development, differentiation, and maintenance of a number of tissue types (1).

Reference
1. Uwanogho, D.A., Hardcastle, Z., Balogh, P., Mirza, G., Thornburg, K.L., Ragoussis, J. and Sharpe, P.T. (1999) Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene. Genomics, 62, 406-416. PMID: 10644438


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusEKPD IDGene IDGene Name
1
EPS-GAA-00173
ENSGACG00000004096
PTPLA
2
EPS-GAA-00175
ENSGACG00000001232
PTPLB
3
EPS-GAA-00174
ENSGACG00000000890
PTPLAD2
4
EPS-GAA-00171
ENSGACG00000017047
PTPLAD1 (1 of 2)
5
EPS-GAA-00172
ENSGACG00000004806
PTPLAD1 (2 of 2)