Monodelphis domestica      PTPLA      PTPLA

※ PTPLA family introduction

    PTPLA, Protein tyrosine phosphatase-like protein, contains protein tyrosine phosphatase-like proteins. Classical PTP is characterized by its signure motif CXXXXXR, however, the Arg to Pro(R/P) variation is found at active site in PTPLA. And PTPLA have been thought to play an important role in development, differentiation, and maintenance of a number of tissue types (1).

Reference
1. Uwanogho, D.A., Hardcastle, Z., Balogh, P., Mirza, G., Thornburg, K.L., Ragoussis, J. and Sharpe, P.T. (1999) Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene. Genomics, 62, 406-416. PMID: 10644438


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusEKPD IDGene IDGene Name
1
EPS-MOD-00112
ENSMODG00000003655
PTPLAD2
2
EPS-MOD-00109
ENSMODG00000009893
PTPLAD1
3
EPS-MOD-00111
ENSMODG00000009722
PTPLA
4
EPS-MOD-00110
ENSMODG00000018338
PTPLB