Pongo abelii      PTPLA      PTPLA

※ PTPLA family introduction

    PTPLA, Protein tyrosine phosphatase-like protein, contains protein tyrosine phosphatase-like proteins. Classical PTP is characterized by its signure motif CXXXXXR, however, the Arg to Pro(R/P) variation is found at active site in PTPLA. And PTPLA have been thought to play an important role in development, differentiation, and maintenance of a number of tissue types (1).

Reference
1. Uwanogho, D.A., Hardcastle, Z., Balogh, P., Mirza, G., Thornburg, K.L., Ragoussis, J. and Sharpe, P.T. (1999) Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene. Genomics, 62, 406-416. PMID: 10644438


There are 4 genes.  Reviewed (2 or Unreviewed (2

No.StatusEKPD IDGene IDGene Name
1
EPS-POA-00124
ENSPPYG00000013472
PTPLB; HACD2
2
EPS-POA-00127
ENSPPYG00000019186
PTPLAD2
3
EPS-POA-00126
ENSPPYG00000006569
HACD3; PTPLAD1
4
EPS-POA-00125
ENSPPYG00000002125
PTPLA