Rattus norvegicus      PTPLA      PTPLA

※ PTPLA family introduction

    PTPLA, Protein tyrosine phosphatase-like protein, contains protein tyrosine phosphatase-like proteins. Classical PTP is characterized by its signure motif CXXXXXR, however, the Arg to Pro(R/P) variation is found at active site in PTPLA. And PTPLA have been thought to play an important role in development, differentiation, and maintenance of a number of tissue types (1).

Reference
1. Uwanogho, D.A., Hardcastle, Z., Balogh, P., Mirza, G., Thornburg, K.L., Ragoussis, J. and Sharpe, P.T. (1999) Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene. Genomics, 62, 406-416. PMID: 10644438


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusEKPD IDGene IDGene Name
1
EPS-RAN-00112
ENSRNOG00000038761
Ptplb
2
EPS-RAN-00113
ENSRNOG00000030232
Ptplad1
3
EPS-RAN-00114
ENSRNOG00000005772
Ptplad2_predicted; Ptplad2; rCG_23010
4
EPS-RAN-00111
ENSRNOG00000043192
Ptpla