Ciona intestinalis      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family

There are 3 genes.  Reviewed (0)  or Unreviewed (3) 

No.StatusEKPD IDGene IDGene Name
1
EKS-CII-00218
ENSCING00000014087
Ci-MAPKKK4; CI-MAPKKK4
2
EKS-CII-00217
ENSCING00000008410
3
EKS-CII-00219
ENSCING00000012975
Cin.26880; CIN.26880