Felis catus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-FEC-00374
ENSFCAG00000003496
MAP3K3
2
EKS-FEC-00375
ENSFCAG00000006993
MAP3K2
3
EKS-FEC-00377
ENSFCAG00000012906
MAP3K15
4
EKS-FEC-00381
ENSFCAG00000007864
MAP3K6
5
EKS-FEC-00376
ENSFCAG00000008186
6
EKS-FEC-00379
ENSFCAG00000026221
MAP3K19
7
EKS-FEC-00378
ENSFCAG00000000356
MAP3K4
8
EKS-FEC-00380
ENSFCAG00000014104
MAP3K1