Xiphophorus maculatus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-XIM-00492
ENSXMAG00000009609
MAP3K4
2
EKS-XIM-00493
ENSXMAG00000016278
MAP3K5 (3 of 3)
3
EKS-XIM-00488
ENSXMAG00000003618
MAP3K15
4
EKS-XIM-00489
ENSXMAG00000014853
MAP3K6
5
EKS-XIM-00494
ENSXMAG00000002035
MAP3K19
6
EKS-XIM-00490
ENSXMAG00000006312
MAP3K2
7
EKS-XIM-00487
ENSXMAG00000008111
MAP3K3
8
EKS-XIM-00491
ENSXMAG00000009286