Latimeria chalumnae      TK      Lmr

※ Lmr family introduction

    Lmr (Lemur tyrosine kinase) belong to tyrosine kinase family (1). Three members have been found in human genome. LMTK1, also known as AATK, is an apoptosis-associated tyrosine kinase; it contains an N-terminal tyrosine kinase domain and a C-terminal proline-rich domain. LMTK1 is required for induction of growth arrest or apoptosis of myeloid precursor cells. LMTK2 is thought to mediate the phosphorylation of PPP1C. Function and regulation LMTK3 remain further understood (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikipedia annotation:    AATK


There are 3 genes.  Reviewed (0 or Unreviewed (3

No.StatusEKPD IDGene IDGene Name
1
EKS-LAC-00377
ENSLACG00000014438
AATK
2
EKS-LAC-00378
ENSLACG00000013999
LMTK2
3
EKS-LAC-00379
ENSLACG00000004698
LMTK3