Tetraodon nigroviridis      TK      Lmr

※ Lmr family introduction

    Lmr (Lemur tyrosine kinase) belong to tyrosine kinase family (1). Three members have been found in human genome. LMTK1, also known as AATK, is an apoptosis-associated tyrosine kinase; it contains an N-terminal tyrosine kinase domain and a C-terminal proline-rich domain. LMTK1 is required for induction of growth arrest or apoptosis of myeloid precursor cells. LMTK2 is thought to mediate the phosphorylation of PPP1C. Function and regulation LMTK3 remain further understood (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikipedia annotation:    AATK


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusEKPD IDGene IDGene Name
1
EKS-TEN-00458
ENSTNIG00000009791
AATK (2 of 2); AATK (1 of 2)
2
EKS-TEN-00461
ENSTNIG00000008084
GSTENG00015398001; LMTK3
3
EKS-TEN-00459
ENSTNIG00000011881
AATK (2 of 2); AATK (1 of 2)
4
EKS-TEN-00460
ENSTNIG00000011950
LMTK2