※ MLK family introduction

    MLKs (Mixed-lineage kinases) are ser/thr protein kinases which are involved in regulation of JNK and p38 MAPK pathways. MLKs contains threes subfamily, MLK, DLK and ZAK. MLK subfamily is characterized by an N-terminal SH3 domain, followed by a protein kinase domain, a leucine-zipper region and a CRIB motif. DLK subfamily contains a kinase domain and two leucine-zipper motifs. ZAK subfamily consists of a kinase domain and a SAM domain. MLKs play an important role in regulation of JNK pathways in mammalian cells which will result in diverse biological processes, including cellular transformation, activation of NF-kB pathways, neuronal apoptosis and so on (1).

Reference
1. Gallo, K.A. and Johnson, G.L. (2002) Mixed-lineage kinase control of JNK and p38 MAPK pathways. Nat Rev Mol Cell Biol, 3, 663-672. PMID: 12209126

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SOL-01078	Solyc07g006760.2	Solyc07g006760.2
2		EKS-SOL-01059	Solyc12g094410.1	Solyc12g094410.1
3		EKS-SOL-01075	Solyc07g007140.2	Solyc07g007140.2
4		EKS-SOL-01084	Solyc02g091170.2	Solyc02g091170.2
5		EKS-SOL-01080	Solyc12g016140.1	Solyc12g016140.1
6		EKS-SOL-01066	Solyc12g009340.1	Solyc12g009340.1
7		EKS-SOL-01061	Solyc07g042890.2	Solyc07g042890.2
8		EKS-SOL-01074	Solyc02g078140.2	Solyc02g078140.2
9		EKS-SOL-01076	Solyc09g091460.2	Solyc09g091460.2
10		EKS-SOL-01079	Solyc06g082190.2	Solyc06g082190.2
11		EKS-SOL-01058	Solyc02g083290.2	Solyc02g083290.2
12		EKS-SOL-01069	Solyc11g012050.1	Solyc11g012050.1
13		EKS-SOL-01073	Solyc01g097980.2	TCTR2
14		EKS-SOL-01056	Solyc01g111880.2	Solyc01g111880.2
15		EKS-SOL-01072	Solyc03g006400.2	Solyc03g006400.2
16		EKS-SOL-01081	Solyc10g045270.1	Solyc10g045270.1
17		EKS-SOL-01071	Solyc04g076480.2	Solyc04g076480.2
18		EKS-SOL-01082	Solyc12g016070.1	Solyc12g016070.1
19		EKS-SOL-01065	Solyc08g065250.2	Solyc08g065250.2
20		EKS-SOL-01062	Solyc10g083610.1	ER50
21		EKS-SOL-01068	Solyc03g119140.2	Solyc03g119140.2
22		EKS-SOL-01057	Solyc10g055720.1	Solyc10g055720.1
23		EKS-SOL-01067	Solyc10g085570.1	CTR4
24		EKS-SOL-01070	Solyc06g068980.2	Solyc06g068980.2
25		EKS-SOL-01077	Solyc02g093410.2	Solyc02g093410.2
26		EKS-SOL-01064	Solyc04g014690.2	Solyc04g014690.2
27		EKS-SOL-01063	Solyc09g009090.2	CTR3
28		EKS-SOL-01083	Solyc04g026210.2	Solyc04g026210.2
29		EKS-SOL-01060	Solyc07g042680.2	Solyc07g042680.2