※ MLK family introduction

    MLKs (Mixed-lineage kinases) are ser/thr protein kinases which are involved in regulation of JNK and p38 MAPK pathways. MLKs contains threes subfamily, MLK, DLK and ZAK. MLK subfamily is characterized by an N-terminal SH3 domain, followed by a protein kinase domain, a leucine-zipper region and a CRIB motif. DLK subfamily contains a kinase domain and two leucine-zipper motifs. ZAK subfamily consists of a kinase domain and a SAM domain. MLKs play an important role in regulation of JNK pathways in mammalian cells which will result in diverse biological processes, including cellular transformation, activation of NF-kB pathways, neuronal apoptosis and so on (1).

Reference
1. Gallo, K.A. and Johnson, G.L. (2002) Mixed-lineage kinase control of JNK and p38 MAPK pathways. Nat Rev Mol Cell Biol, 3, 663-672. PMID: 12209126

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No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SOB-01189	Sb03g008630	SORBIDRAFT_03g008630; Sb03g008630; SB03G008630
2		EKS-SOB-01211	Sb06g031750
3		EKS-SOB-01204	Sb02g039310	SORBIDRAFT_02g039310; SB02G039310; Sb02g039310
4		EKS-SOB-01206	Sb10g024900	SORBIDRAFT_10g024900; Sb10g024900; SB10G024900
5		EKS-SOB-01208	Sb09g004060	SB09G004060; Sb09g004060; SORBIDRAFT_09g004060
6		EKS-SOB-01191	Sb07g000410	Sb07g000410; SB07G000410; SORBIDRAFT_07g000410
7		EKS-SOB-01199	Sb07g020260	Sb07g020260; SB07G020260; SORBIDRAFT_07g020260
8		EKS-SOB-01205	Sb01g003640
9		EKS-SOB-01210	Sb10g005460	SORBIDRAFT_10g005460; SB10G005460; Sb10g005460
10		EKS-SOB-01202	Sb09g025830	SORBIDRAFT_09g025830; Sb09g025830; SB09G025830
11		EKS-SOB-01213	Sb10g025430	Sb10g025430; SB10G025430; SORBIDRAFT_10g025430
12		EKS-SOB-01195	Sb04g021500	SB04G021500; SORBIDRAFT_04g021500; Sb04g021500
13		EKS-SOB-01198	Sb01g046460	SORBIDRAFT_01g046460; Sb01g046460; SB01G046460
14		EKS-SOB-01196	Sb04g028160	Sb04g028160; SORBIDRAFT_04g028160; SB04G028160
15		EKS-SOB-01200	Sb03g002580	Sb03g002580; SORBIDRAFT_03g002580; SB03G002580
16		EKS-SOB-01197	Sb02g033100	SORBIDRAFT_02g033100; Sb02g033100; SB02G033100
17		EKS-SOB-01215	Sb01g038280	SB01G038280; Sb01g038280; SORBIDRAFT_01g038280
18		EKS-SOB-01212	Sb04g035290
19		EKS-SOB-01194	Sb06g027970	SORBIDRAFT_06g027970; Sb06g027970; SB06G027970
20		EKS-SOB-01201	Sb03g034440	SB03G034440; Sb03g034440; SORBIDRAFT_03g034440
21		EKS-SOB-01203	Sb08g020040	Sb08g020040; SORBIDRAFT_08g020040; SB08G020040
22		EKS-SOB-01190	Sb07g006320	SORBIDRAFT_07g006320; SB07G006320; Sb07g006320
23		EKS-SOB-01193	Sb07g006310	SORBIDRAFT_07g006310; SB07G006310; Sb07g006310
24		EKS-SOB-01188	Sb02g011690	SORBIDRAFT_02g011690; Sb02g011690; SB02G011690
25		EKS-SOB-01192	Sb04g004950	Sb04g004950; SORBIDRAFT_04g004950; SB04G004950
26		EKS-SOB-01209	Sb04g024680	Sb04g024680; SORBIDRAFT_04g024680; SB04G024680
27		EKS-SOB-01207	Sb01g000310	SORBIDRAFT_01g000310; Sb01g000310; SB01G000310
28		EKS-SOB-01214	Sb10g008270	Sb10g008270; SB10G008270; SORBIDRAFT_10g008270