EPS-POA-00043
Eukaryotic Protein Kinase & Protein Phosphatase Database
TagContent
EKPD IDEPS-POA-00043
Classification
Group/FamilyScoreE-ValueStartEndDomain Length
DSP/CDC14205.21.7E-61250360111
StatusUnreviewed
Ensembl ProteinENSPPYP00000021757
UniProt AccessionH2PST4;
Protein Name
Protein Synonyms/Alias
Gene NameCDC14B
Gene Synonyms/Alias CDC14B;
Ensembl Information
Ensembl Gene IDEnsembl Protein IDEnsembl Transcript ID
ENSPPYG00000019417ENSPPYP00000021757ENSPPYT00000022647
OrganismPongo abelii
Functional Description
Protein Length498
Protein Sequence
(FASTA)
MKRKSERRSS WAAAPPCSRR CSSTSPGVKK IRSSTQQDPR RRDPQDDVYL DITDRLCFAI 60
LYSRPKSASN VHYFSIDNEL EYENFYADFG PLNLAMVYRY CCKINKKLKS ITMLRKKIVH 120
FTGSDQRKQA NAAFLVGCYM VIYLGRTPEE AYRILIFGET SYIPFRDAAY GSCNFYITLL 180
DCFHAVKKAM QYGFLNFNSF NLDEYEHYEK AENGDLNWII PDRFIAFCGP HSRARLESGY 240
HQHSPETYIQ YFKNHNVTTI IRLNKRMYDA KRFTDAGFDH HDLFFADGST PTDAIVKEFL 300
DICENAEGAI AVHCKAGLGR TGTLIACYIM KHYRMTAAET IAWVRICRPG SVIGPQQQFL 360
VMKQTNLWLE GDYFRQKLKG QENGQHRAAF SKLLSGVDDI SINGVENQDQ QEPEPYSDDD 420
EINGVTQGDR LRALKSRRQS KTNAIPLTVI LQSSVQSCKT SEPNISGSAG ITKRTTRSAS 480
RKSSVKSLSI SRTKTVLR 498
Nucleotide Sequence
(FASTA)
ATGAAGCGGA AAAGCGAGCG GCGGTCGAGC TGGGCCGCCG CGCCCCCCTG CTCGCGGCGC 60
TGCTCGTCTA CCTCGCCGGG TGTGAAGAAG ATCCGCAGCT CCACGCAGCA AGACCCGCGC 120
CGCCGGGACC CCCAGGACGA CGTGTACCTG GACATCACCG ATCGCCTTTG TTTTGCCATT 180
CTCTACAGCA GACCAAAGAG TGCATCAAAT GTACATTATT TCAGCATAGA TAATGAACTT 240
GAATATGAGA ACTTCTACGC AGATTTTGGA CCACTCAATC TGGCAATGGT TTACAGATAT 300
TGTTGCAAGA TAAATAAGAA ATTAAAGTCC ATTACAATGT TAAGGAAGAA AATTGTTCAT 360
TTTACTGGCT CTGATCAGAG AAAACAAGCA AATGCTGCCT TCCTTGTTGG ATGCTACATG 420
GTTATATATT TGGGGAGAAC CCCAGAAGAA GCATATAGAA TATTAATCTT TGGAGAGACA 480
TCCTATATTC CTTTCAGAGA TGCTGCCTAT GGAAGTTGCA ATTTCTACAT TACACTTCTT 540
GACTGTTTTC ATGCAGTAAA GAAGGCAATG CAGTATGGCT TCCTTAATTT CAACTCATTT 600
AACCTTGATG AATATGAACA CTATGAAAAA GCAGAAAATG GAGATTTAAA TTGGATAATA 660
CCAGACCGAT TTATTGCCTT CTGTGGACCT CATTCAAGAG CCAGACTTGA AAGTGGCTAC 720
CACCAACATT CTCCTGAGAC TTATATTCAA TATTTTAAGA ATCACAATGT TACTACCATT 780
ATTCGTCTGA ATAAAAGGAT GTATGATGCC AAACGCTTTA CGGATGCTGG CTTCGATCAC 840
CATGATCTTT TCTTTGCGGA TGGCAGCACC CCTACTGATG CCATTGTCAA AGAATTCCTG 900
GATATCTGTG AAAATGCTGA GGGTGCCATT GCAGTACATT GTAAAGCTGG CCTTGGTCGC 960
ACGGGCACTC TGATAGCCTG CTACATCATG AAGCATTACA GGATGACAGC AGCCGAGACC 1020
ATTGCGTGGG TCAGGATCTG CAGACCTGGC TCGGTGATTG GGCCTCAGCA GCAGTTTTTG 1080
GTGATGAAGC AAACAAACCT CTGGCTGGAA GGAGACTATT TTCGTCAGAA GTTAAAGGGT 1140
CAGGAGAATG GACAACACAG AGCAGCCTTC TCCAAACTTC TCTCTGGCGT TGATGACATT 1200
TCCATAAATG GGGTCGAGAA TCAAGATCAG CAAGAACCCG AACCGTACAG TGATGATGAC 1260
GAAATCAATG GAGTGACACA AGGTGATAGA CTTCGGGCCT TGAAAAGCAG AAGACAATCC 1320
AAAACAAACG CTATTCCTCT CACAGTAATT CTTCAATCCA GTGTTCAGAG CTGTAAAACA 1380
TCTGAACCTA ACATTTCTGG CAGTGCAGGC ATTACTAAAA GAACCACCAG ATCTGCTTCA 1440
AGGAAAAGCA GTGTTAAAAG TCTCTCCATT TCAAGGACTA AAACAGTCTT GCGTTAA 1497
Domain Profile
S: 1     nffknnnvtlvvrlnkklydkkrfedvgiehkdllfedgtvpelsivkefldiaenteGa  60
         ++fkn+nvt+++rlnk++yd+krf+d+g++h+dl+f+dg++p+++ivkefldi+en+eGa
Q: 250   QYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICENAEGA  309
         69**********************************************************
S: 61    iavhckaGlGrtGtliaaylikkyrltaaeviaflriirpGsvvGpqqhfl  111
         iavhckaGlGrtGtlia+y++k+yr+taae+ia++ri+rpGsv+Gpqq+fl
Q: 310   IAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL  360
         **************************************************8
Domain Sequence
(FASTA)
QYFKNHNVTT IIRLNKRMYD AKRFTDAGFD HHDLFFADGS TPTDAIVKEF LDICENAEGA 60
IAVHCKAGLG RTGTLIACYI MKHYRMTAAE TIAWVRICRP GSVIGPQQQF L 111
KeywordComplete proteome; Hydrolase; Reference proteome.
Sequence SourceEnsembl
Orthology
Ortholog group
Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>
EPS-AIM-00041
EPS-BOT-00037
EPS-CAJ-00036
EPS-CAF-00046
EPS-CAP-00035
EPS-FEC-00043
EPS-GAG-00039
EPS-GOG-00043
EPS-HOS-00036
EPS-LOA-00034
EPS-MAM-00036
EPS-MOD-00036
EPS-MUM-00036
EPS-MUP-00033
EPS-MYL-00038
EPS-NOL-00041
EPS-ORC-00036
EPS-OTG-00038
EPS-PAT-00035
EPS-PES-00044
EPS-RAN-00039
EPS-SAH-00036
EPS-SUS-00034
EPS-TAG-00039
EPS-TUT-00027
EPS-XET-00041
Gene Ontology
GO:0005730; C:nucleolus
GO:0005654; C:nucleoplasm
GO:0004722; F:protein serine/threonine phosphatase activity
GO:0004725; F:protein tyrosine phosphatase activity
GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity
GO:0051488; P:activation of anaphase-promoting complex activity
GO:0031572; P:G2/M transition DNA damage checkpoint
KEGG
pon:100436806;
InterPros
IPR000340; Dual-sp_phosphatase_cat-dom.
IPR020422; Dual-sp_phosphatase_subgr_cat.
IPR026068; Dual_Pase_CDC14.
IPR000387; Tyr/Dual-specificity_Pase.
IPR016130; Tyr_Pase_AS.
Pfam
PF00782; DSPc; 1.
SMARTs
Prosites
PS00383; TYR_PHOSPHATASE_1; 1.
PS50056; TYR_PHOSPHATASE_2; 1.
PS50054; TYR_PHOSPHATASE_DUAL; 1.
Prints
Created Date20-Feb-2013