EKS-ART-00941

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ART-00941

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PKA	181.8	2.7E-53	785	1035	251

Status

Reviewed

Ensembl Protein

AT2G20050.2

UniProt Accession

Q9SL76; B5KQ16; B5KQ17; Q0WLT6; Q9SL77;

Protein Name

Probable inactive cyclic nucleotide-dependent protein kinase At2g20050

Protein Synonyms/Alias

AtPP2C19;

Gene Name

AT2G20050

Gene Synonyms/Alias

At2g20050; T2G17.15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
AT2G20050	AT2G20050.1	AT2G20050.1
AT2G20050	AT2G20050.2	AT2G20050.2

Organism

Arabidopsis thaliana

Functional Description

Protein Length

1091

Protein Sequence
(FASTA)

MGCAYSKTCI GQICATKENS IRQTHQQAPS RGGTRATAAA AAVEEDNPVF NFSSDAVDDV 60

DNDEIHQLGL SRDQEWGITR LSRVSSQFLP PDGSRVVKVP SCNYELRCSF LSQRGYYPDA 120

LDKANQDSFA IHTPFGSNSD DHFFGVFDGH GEFGAQCSQF VKRRLCENLL RHGRFRVDPA 180

EACNSAFLTT NSQLHADLVD DSMSGTTAIT VMVRGRTIYV ANAGDSRAVL AEKRDGDLVA 240

VDLSIDQTPF RPDELERVKL CGARVLTLDQ IEGLKNPDVQ CWGTEEDDDG DPPRLWVPNG 300

MYPGTAFTRS IGDSIAETIG VVANPEIAVV ELTPDNPFFV VASDGVFEFI SSQTVVDMVA 360

KHKDPRDACA AIVAESYRLW LQYETRTDDI TIIVVHIDGL KDDAPRQLSS TGTQLQPPIP 420

QVVELTGSES PSTFGWNSKN QRVRHDLSRA RIRAIENSLE NGHAWVPPSP AHRKTWEEEA 480

HIERVLRDHF LFRKLTDSQC QVLLDCMQRL EANPGDIVVK QGGEGDCFYV VGSGEFEVLA 540

TQNGEVPRIL QRYTAEKQSS FGELALMHNK PLQASVRAVD HGTLWALKRE DFRGILMSEF 600

SNLASLKLLR SVDLLSRLTI LQLSHVAESL SEACFSDGQT IVTKDQKLQG LYVIQKGRVK 660

ISFCTEVLES QNVSSLTTGI TNEYDNLEIG TEVSIEKHEG SYFGEWALLG ELKDSLSVVA 720

VGEVVCVVLT KENFESAVGP LTNISDDGPK TRHSSFELSK ESAKVTDTTA LAKATLADLE 780

WTTCLSTTDC SEIGLVHLKD KENLLSLKRF SKQKVKKLGK EAQVLKERNL MKNVIKPSAI 840

VPEILCTCVD QTFAAILLNT TLACPISSLL HSPLDESSVR FITGSLVSAI EDIHKNEILF 900

RGSSPELLML DQSGYLQIVD FRFAKKLSGE RTFTICGNAD YLAPEIVQGK GHGYAADWWA 960

LGVLIYYMLE GEMPFGSWRE SELDTFQKIA KGQLTFPRVL SSEAEDLITK LLEVDENLRF 1020

GSQGGPESIK KHPWFNGLKW EAISNREFQV PQEIISRIHH HLENDNVLPL ETSKSLDTTE 1080

DQDAQNWLEE W 1091

Nucleotide Sequence
(FASTA)

ATGGGTTGTG CTTATTCCAA AACTTGCATT GGTCAGATTT GTGCTACGAA AGAGAATAGT 60

ATCAGGCAAA CGCATCAACA AGCTCCGTCC AGAGGTGGCA CGAGAGCTAC TGCGGCGGCG 120

GCGGCGGTTG AGGAGGATAA TCCGGTGTTT AATTTCTCTT CAGATGCGGT GGATGATGTA 180

GATAACGACG AAATTCATCA GCTTGGTTTG AGTAGAGACC AGGAATGGGG GATTACTCGG 240

CTTTCTAGGG TTTCTTCTCA ATTTCTACCA CCAGATGGGT CAAGGGTTGT CAAGGTTCCG 300

TCTTGTAACT ATGAATTGAG ATGCTCGTTT TTGTCTCAAA GAGGGTATTA TCCTGATGCT 360

CTTGATAAGG CCAATCAAGA TAGTTTCGCT ATTCATACTC CTTTTGGGAG TAATTCGGAT 420

GATCATTTCT TTGGGGTTTT TGATGGGCAT GGTGAGTTTG GTGCTCAGTG TTCTCAGTTT 480

GTGAAGCGGA GGTTGTGTGA GAATCTTCTT AGACATGGTA GGTTTCGTGT GGATCCTGCT 540

GAGGCTTGTA ATTCGGCTTT CTTGACCACG AATTCTCAGT TACATGCTGA TTTGGTAGAT 600

GATAGTATGA GTGGGACTAC TGCGATTACG GTTATGGTTA GAGGAAGGAC GATATATGTG 660

GCGAATGCAG GTGATTCCAG GGCGGTTTTA GCTGAGAAGA GGGATGGTGA TCTTGTAGCT 720

GTTGATTTGT CTATTGACCA GACTCCTTTT AGACCTGATG AGCTTGAAAG GGTTAAGCTT 780

TGTGGTGCTA GAGTTCTTAC TCTTGATCAG ATTGAAGGCT TGAAAAATCC TGATGTTCAG 840

TGTTGGGGTA CTGAGGAAGA TGATGATGGA GACCCTCCGA GACTTTGGGT GCCTAATGGA 900

ATGTATCCTG GAACTGCTTT TACCAGGAGT ATTGGTGATT CTATTGCAGA GACAATTGGT 960

GTTGTTGCTA ACCCTGAGAT TGCTGTTGTT GAGCTCACAC CGGATAATCC TTTCTTTGTG 1020

GTTGCTAGTG ATGGCGTATT TGAGTTCATC TCTAGTCAAA CGGTGGTTGA CATGGTTGCA 1080

AAACATAAGG ATCCTCGAGA TGCTTGTGCT GCAATTGTTG CTGAATCATA TAGGCTATGG 1140

CTACAGTATG AAACTCGGAC AGATGATATA ACAATCATCG TCGTGCACAT TGATGGACTA 1200

AAAGATGATG CTCCTCGGCA ATTGTCGAGT ACAGGAACTC AATTGCAGCC TCCTATTCCA 1260

CAAGTTGTGG AGCTTACAGG TTCGGAATCT CCTTCCACCT TTGGATGGAA CTCTAAAAAT 1320

CAACGTGTGA GGCATGATCT ATCTCGAGCT AGGATACGTG CCATTGAGAA TTCACTAGAG 1380

AATGGACATG CTTGGGTTCC TCCATCTCCA GCCCACAGAA AAACCTGGGA AGAAGAAGCA 1440

CACATTGAGC GGGTGTTGCG TGACCATTTC CTCTTCAGGA AACTCACTGA TTCTCAGTGC 1500

CAGGTTTTGT TGGACTGCAT GCAAAGGCTT GAAGCTAATC CAGGGGATAT TGTTGTGAAA 1560

CAGGGTGGTG AAGGGGACTG CTTCTACGTT GTGGGTAGTG GAGAATTCGA GGTCTTAGCA 1620

ACTCAGAACG GTGAGGTACC TAGGATCTTG CAGCGTTATA CAGCTGAGAA ACAATCATCA 1680

TTCGGTGAAC TCGCCTTAAT GCATAACAAG CCGCTTCAGG CTTCTGTACG TGCTGTAGAT 1740

CACGGAACAT TGTGGGCCTT AAAAAGAGAA GATTTTCGAG GAATTTTGAT GTCTGAGTTT 1800

TCAAACTTAG CATCCTTGAA GCTTCTTCGT TCTGTCGATC TTCTTTCCCG TCTTACAATT 1860

TTGCAACTAA GCCATGTTGC AGAGTCTCTT TCCGAAGCTT GCTTTTCTGA TGGACAAACA 1920

ATTGTTACCA AGGACCAAAA ACTTCAGGGC CTGTATGTTA TCCAGAAGGG ACGCGTAAAA 1980

ATATCTTTCT GTACAGAGGT GTTGGAGAGT CAAAATGTTT CAAGCCTTAC AACTGGAATC 2040

ACTAACGAGT ATGACAATCT TGAAATCGGA ACAGAAGTCT CCATAGAAAA GCATGAAGGA 2100

AGTTACTTTG GTGAATGGGC TCTTCTTGGC GAACTCAAAG ATTCCTTAAG TGTGGTTGCA 2160

GTTGGCGAAG TGGTTTGTGT GGTTTTAACA AAAGAAAATT TCGAGTCAGC GGTCGGCCCT 2220

CTGACCAATA TTTCAGATGA CGGTCCCAAG ACAAGACATT CTTCATTCGA GCTGTCAAAG 2280

GAATCTGCAA AAGTTACCGA TACCACAGCT CTTGCTAAAG CCACTCTTGC AGACCTGGAA 2340

TGGACAACAT GCTTGAGTAC AACAGACTGT AGTGAGATTG GGCTCGTGCA TTTGAAAGAT 2400

AAAGAAAATT TGCTCAGCTT GAAAAGATTT TCAAAGCAAA AGGTGAAAAA GTTAGGTAAA 2460

GAGGCACAAG TATTGAAAGA GCGGAATCTG ATGAAGAACG TAATAAAGCC CTCAGCTATT 2520

GTTCCCGAAA TCTTGTGTAC TTGTGTCGAT CAAACATTTG CGGCAATCTT ACTGAACACT 2580

ACTCTTGCCT GTCCTATCTC TTCTCTGCTT CACTCTCCGC TTGACGAGTC ATCTGTCCGT 2640

TTCATTACCG GCTCACTTGT GTCTGCCATA GAAGACATAC ACAAGAACGA GATTCTCTTC 2700

AGAGGTTCAT CCCCCGAGTT ACTGATGTTG GATCAATCCG GATATCTACA GATTGTAGAC 2760

TTCAGATTCG CCAAGAAATT GTCCGGGGAA CGAACATTTA CAATCTGTGG AAATGCAGAT 2820

TATTTAGCCC CAGAAATTGT TCAAGGCAAA GGCCATGGTT ATGCAGCTGA CTGGTGGGCT 2880

CTTGGAGTTT TGATCTACTA TATGCTAGAA GGAGAAATGC CATTCGGGTC ATGGAGAGAG 2940

AGCGAGCTCG ACACGTTTCA GAAGATTGCA AAAGGCCAAC TAACTTTCCC TCGAGTTCTA 3000

AGCTCAGAAG CTGAAGATCT CATCACAAAG TTGCTTGAAG TTGATGAAAA CCTGCGGTTT 3060

GGTAGCCAAG GAGGTCCAGA ATCAATCAAG AAACATCCCT GGTTCAATGG TCTTAAATGG 3120

GAAGCTATTA GTAACCGCGA ATTTCAAGTT CCTCAAGAGA TAATCTCGCG AATTCATCAC 3180

CATTTGGAGA ATGATAACGT TCTCCCTCTA GAAACTTCTA AATCGCTTGA CACAACAGAA 3240

GATCAAGATG CTCAAAACTG GCTTGAAGAA TGGTAA 3276

Domain Profile

S: 7     lGtGsfGrvelvrekeskkyyalkvlskekvvklkqvehvknekrvlkavefpflv..kl  64

         l t     + lv+ k +++  +lk +sk+kv kl + + v +e++++k+v  p  +  ++

Q: 785   LSTTDCSEIGLVHLKDKENLLSLKRFSKQKVKKLGKEAQVLKERNLMKNVIKPSAIvpEI  844

         55666678889999**************************************98773467

S: 65    lasfkdesnlylvleyveGGelfsylrkvrrfsekaarfyaaeivlaleylhsldliyrd  124

         l ++ d+++  ++l+      + s+l+    + e+  rf +  +v a+e +h+ ++++r

Q: 845   LCTCVDQTFAAILLNTTLACPISSLLHS--PLDESSVRFITGSLVSAIEDIHKNEILFRG  902

         8888888889999999999999999975..689999************************

S: 125   lkpenllldkeGyikvtdfGfakkvk.drtwtlcGtpeylapeiiqskgynkavdwwalG  183

           pe l+ld++Gy+++ df fakk++ +rt+t+cG  +ylapei+q kg++ a dwwalG

Q: 903   SSPELLMLDQSGYLQIVDFRFAKKLSgERTFTICGNADYLAPEIVQGKGHGYAADWWALG  962

         *************************8359*******************************

S: 184   vliyellaGyppf..fddqpikiyekivsgklkfpsklssdlkdllkkllqvdltkrlgn  241

         vliy +l G  pf  + ++ +++++ki +g+l+fp+ lss+++dl++kll+vd   r+g+

Q: 963   VLIYYMLEGEMPFgsWRESELDTFQKIAKGQLTFPRVLSSEAEDLITKLLEVDENLRFGS  1022

         *************9889999***************************************8

S: 242   lkngvedikehkwf  255

          + g e ik+h wf

Q: 1023  -QGGPESIKKHPWF  1035

         .789*********9

Domain Sequence
(FASTA)

LSTTDCSEIG LVHLKDKENL LSLKRFSKQK VKKLGKEAQV LKERNLMKNV IKPSAIVPEI 60

LCTCVDQTFA AILLNTTLAC PISSLLHSPL DESSVRFITG SLVSAIEDIH KNEILFRGSS 120

PELLMLDQSG YLQIVDFRFA KKLSGERTFT ICGNADYLAP EIVQGKGHGY AADWWALGVL 180

IYYMLEGEMP FGSWRESELD TFQKIAKGQL TFPRVLSSEA EDLITKLLEV DENLRFGSQG 240

GPESIKKHPW F 251

Keyword

Alternative splicing; ATP-binding; Complete proteome; Hydrolase; Kinase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Phosphoprotein; Protein phosphatase; Reference proteome; Repeat; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Glycine max"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Physcomitrella patens"; ?>Populus trichocarpa"; ?>Selaginella moellendorffii"; ?>Setaria italica"; ?>Solanum lycopersicum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005952	; C:cAMP-dependent protein kinase complex
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0008603	; F:cAMP-dependent protein kinase regulator activity
GO:0046872	; F:metal ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

ath:AT2G20050

;

InterPros

IPR002373	; cAMP/cGMP_kin.
IPR018490	; cNMP-bd-like.
IPR000595	; cNMP-bd_dom.
IPR011009	; Kinase-like_dom.
IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR000719	; Prot_kinase_cat_dom.
IPR015655	; Protein_Pase_2C.
IPR014710	; RmlC-like_jellyroll.

Pfam

PF00027	; cNMP_binding; 2.
PF00069	; Pkinase; 1.
PF00481	; PP2C; 1.

SMARTs

SM00100	; cNMP; 2.
SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS00888	; CNMP_BINDING_1; FALSE_NEG.
PS00889	; CNMP_BINDING_2; FALSE_NEG.
PS50042	; CNMP_BINDING_3; 2.
PS01032	; PP2C; 1.
PS00107	; PROTEIN_KINASE_ATP; FALSE_NEG.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; FALSE_NEG.

Prints

PR00103

; CAMPKINASE.

Created Date

20-Feb-2013