| Tag | Content |
|---|
| EKPD ID | EKS-ART-00974 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| CMGC/MAPK | 407.9 | 3.7E-122 | 67 | 348 | 282 |
|
| Status | Reviewed |
| Ensembl Protein | AT2G43790.1 |
| UniProt Accession | Q39026; |
| Protein Name | Mitogen-activated protein kinase 6 |
| Protein Synonyms/Alias | AtMPK6; MAP kinase 6; |
| Gene Name | MPK6 |
| Gene Synonyms/Alias | MPK6; At2g43790; F18O19.10; |
| Ensembl Information | |
| Organism | Arabidopsis thaliana |
| Functional Description | Involved in oxidative stress-mediated signaling cascade(such as ozone). Involved in the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6) downstream of bacterial flagellin receptor FLS2. May be involved in hypersensitive response (HR)-mediated signaling cascade. May phosphorylate regulators of WRKY transcription factors. Phosphorylates 1-aminocyclopropane-1-carboxylic acid synthases (ACS2 and ACS6) and may be involved in the regulation of bacterial elicitor flagellin-induced ethylene production. Regulates locally gene-mediated and basal resistance response to certain pathogens. May be involved in the cold and salinity stress-mediated MAP kinase signaling cascade (MEKK1, MEK1/MKK2 and MPK4/MPK6). |
| Protein Length | 395 |
Protein Sequence
(FASTA) | | MDGGSGQPAA DTEMTEAPGG FPAAAPSPQM PGIENIPATL SHGGRFIQYN IFGNIFEVTA 60 | | KYKPPIMPIG KGAYGIVCSA MNSETNESVA IKKIANAFDN KIDAKRTLRE IKLLRHMDHE 120 | | NIVAIRDIIP PPLRNAFNDV YIAYELMDTD LHQIIRSNQA LSEEHCQYFL YQILRGLKYI 180 | | HSANVLHRDL KPSNLLLNAN CDLKICDFGL ARVTSESDFM TEYVVTRWYR APELLLNSSD 240 | | YTAAIDVWSV GCIFMELMDR KPLFPGRDHV HQLRLLMELI GTPSEEELEF LNENAKRYIR 300 | | QLPPYPRQSI TDKFPTVHPL AIDLIEKMLT FDPRRRITVL DALAHPYLNS LHDISDEPEC 360 | | TIPFNFDFEN HALSEEQMKE LIYREALAFN PEYQQ 395 |
|
Nucleotide Sequence
(FASTA) | | ATGGACGGTG GTTCAGGTCA ACCGGCGGCT GATACAGAGA TGACAGAAGC TCCTGGAGGT 60 | | TTTCCCGCGG CGGCTCCATC GCCTCAGATG CCTGGGATTG AGAATATTCC GGCGACTCTT 120 | | AGCCATGGTG GTAGGTTTAT TCAGTATAAC ATATTTGGAA ACATCTTCGA GGTCACCGCT 180 | | AAGTATAAGC CTCCGATCAT GCCTATTGGC AAGGGTGCTT ATGGCATCGT TTGTTCGGCT 240 | | ATGAATTCTG AAACTAACGA GAGCGTTGCG ATTAAGAAAA TTGCTAACGC TTTTGACAAT 300 | | AAGATTGATG CTAAGAGGAC TCTCCGTGAG ATCAAGCTGC TTCGTCACAT GGATCATGAA 360 | | AATATTGTTG CAATCAGAGA TATTATCCCG CCACCATTAA GAAACGCTTT CAACGATGTT 420 | | TACATCGCGT ATGAGTTAAT GGACACTGAT CTCCATCAAA TCATTCGGTC AAATCAAGCA 480 | | TTATCCGAAG AACATTGCCA GTATTTTCTT TACCAGATCC TCCGTGGATT GAAATACATT 540 | | CACTCTGCAA ATGTGCTTCA CAGGGATTTG AAACCAAGTA ATCTCCTCCT GAACGCAAAC 600 | | TGCGACCTAA AAATCTGCGA TTTTGGGCTA GCTCGAGTCA CTTCTGAGAG TGATTTCATG 660 | | ACTGAATATG TTGTCACGAG ATGGTACCGT GCACCAGAGC TTCTCTTAAA CTCTTCTGAT 720 | | TATACTGCAG CTATCGATGT TTGGTCTGTA GGCTGTATTT TCATGGAGTT AATGGACCGT 780 | | AAGCCACTCT TCCCTGGACG AGATCATGTC CATCAGCTTC GCTTGCTCAT GGAGCTCATA 840 | | GGAACTCCAT CAGAAGAAGA GCTCGAGTTC TTGAACGAAA ACGCAAAGCG ATACATAAGA 900 | | CAGCTTCCAC CTTATCCTCG CCAATCCATC ACTGATAAGT TCCCGACAGT GCATCCTTTA 960 | | GCTATAGACC TTATCGAGAA GATGTTAACA TTTGATCCTA GACGGAGAAT CACAGTTTTA 1020 | | GACGCATTGG CCCATCCATA CCTGAACTCG TTGCACGACA TAAGCGATGA GCCAGAGTGT 1080 | | ACAATACCTT TCAACTTTGA TTTTGAAAAC CATGCACTCT CAGAGGAGCA GATGAAGGAA 1140 | | CTAATCTACC GCGAGGCGCT TGCTTTCAAT CCAGAATATC AGCAATAG 1188 |
|
| Domain Profile | S: 5 kplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNiikll 64 | p+g+Gayg+v+sa++++t+e+vaikk++++f+++++akrtlRE+kll++++heNi+ + | Q: 67 MPIGKGAYGIVCSAMNSETNESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIR 126 | 689********************************************************* |
| S: 65 dvftpeeeleelkdvYlvtelmetdLkkviksq.klsdehiklllyqilrglkylHsanv 123 | d++ p ++++dvY+ elm+tdL+++i+s+ ls+eh++++lyqilrglky+Hsanv | Q: 127 DIIPPPL-RNAFNDVYIAYELMDTDLHQIIRSNqALSEEHCQYFLYQILRGLKYIHSANV 185 | ***9998.99*********************9989************************* |
| S: 124 iHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslkeytk 183 | +HrDlKPsNll+n++c+lki+dFGlar++++++ +teyv+trwYraPe+ll++++yt | Q: 186 LHRDLKPSNLLLNANCDLKICDFGLARVTSESDF--MTEYVVTRWYRAPELLLNSSDYTA 243 | ****************************998854..************************ |
| S: 184 avDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyiksl 243 | a+D+WsvGCI+ El+ +kplfpg+d+++ql++++e++gtpsee l+ +++ +a++yi++l | Q: 244 AIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEELEFLNE-NAKRYIRQL 302 | **********************************************9999.6******** |
| S: 244 pkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl 289 | p+++++++++ fp+ ++ a+dL+ek+L++dp++Ri+v +aL+hpYl | Q: 303 PPYPRQSITDKFPTVHPLAIDLIEKMLTFDPRRRITVLDALAHPYL 348 | *********************************************7 |
|
Domain Sequence
(FASTA) | | MPIGKGAYGI VCSAMNSETN ESVAIKKIAN AFDNKIDAKR TLREIKLLRH MDHENIVAIR 60 | | DIIPPPLRNA FNDVYIAYEL MDTDLHQIIR SNQALSEEHC QYFLYQILRG LKYIHSANVL 120 | | HRDLKPSNLL LNANCDLKIC DFGLARVTSE SDFMTEYVVT RWYRAPELLL NSSDYTAAID 180 | | VWSVGCIFME LMDRKPLFPG RDHVHQLRLL MELIGTPSEE ELEFLNENAK RYIRQLPPYP 240 | | RQSITDKFPT VHPLAIDLIE KMLTFDPRRR ITVLDALAHP YL 282 |
|
| Keyword | ATP-binding; Complete proteome; Cytoplasm; Hypersensitive response; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Plant defense; Reference proteome; Serine/threonine-protein kinase; Transferase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |