EPS-ART-00023

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ART-00023

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	279.3	6.5E-83	433	807	375

Status

Reviewed

Ensembl Protein

AT2G46920.1

UniProt Accession

Q8RWN7; O80732;

Protein Name

Protein phosphatase 2C 32

Protein Synonyms/Alias

AtPP2C32; Protein POLTERGEIST; Protein phosphatase 2C POL; PP2C POL;

Gene Name

POL

Gene Synonyms/Alias

POL; At2g46920; F14M4.25;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
AT2G46920	AT2G46920.2	AT2G46920.2
AT2G46920	AT2G46920.1	AT2G46920.1

Organism

Arabidopsis thaliana

Functional Description

Involved in the regulation of pedicel length and ofCLAVATA pathways controlling stem cell identity at shoot and flower meristems.

Protein Length

856

Protein Sequence
(FASTA)

MGNGTSRVVG CFVPSNDKNG VDLEFLEPLD EGLGHSFCYV RPSIFESPDI TPSNSERFTI 60

DSSTIDSETL TGSFRNDIVD DPSFLNRHNS KGLAETTFKA ISGASVSANV STARTGNQMA 120

LCSSDVLEPA ASFESTSSFA SIPLQPLPRG GSGPLNGFMS GPLERGFASG PLDRNNGFMS 180

GPIEKGVMSG PLDVSDRSNF SAPLSFRRKK PRFQRFMRSV SGPMKSTLAR TFSRRSGGLS 240

WMHRFFLHPE TRVSWAVGKD GKLHGEDPES CLESNRNLQW AHGKAGEDRV HVVLSEEQGW 300

LFIGIYDGFS GPDAPDFVMS HLYKAIDKEL EGLLWDYEEP SEDNQLQPDQ EPPTEENMCD 360

PESISEQHSK SVVAESEEVM IDDISSLGNT DTQIADGPPG DSAGPGKKSM RLYELLQLEQ 420

WEGEEIGLKR YGGNVALNNM TNQVENPSTS GGGAGNDPCT TDRSALDGIP NSGQRHGTKK 480

SQISSKIRRM YQKQKSLRKK LFPWSYDWHR EEGICVEEKI VESSGPIRRR WSGTVDHDAV 540

LRAMARALES TEEAYMDMVE KSLDINPELA LMGSCVLVML MKDQDVYVMN VGDSRAILAQ 600

ERLHDRHSNP GFGNDEGIGH KSRSRESLVR IELDRISEES PIHNQATPIS VSNKNRDVTS 660

YRLKMRAVQL SSDHSTSVEE EIWRIRSEHP EDDQSILKDR VKGQLKVTRA FGAGFLKKPN 720

FNEALLEMFQ VEYIGTDPYI TCEPCTVHHR LTSSDRFMVL SSDGLYEYFS NEEVVAHVTW 780

FIENVPEGDP AQYLIAELLS RAATKNGMEF HDLLDIPQGD RRKYHDDVSV MVVSLEGRIW 840

RSSGQYYPER KQKFNR 856

Nucleotide Sequence
(FASTA)

ATGGGAAACG GGACTTCCCG TGTTGTTGGT TGTTTCGTGC CGTCTAATGA CAAAAACGGT 60

GTTGATTTGG AGTTTCTGGA ACCTTTAGAT GAAGGTTTAG GCCATTCCTT TTGCTACGTT 120

AGGCCAAGCA TCTTTGAGTC TCCTGATATT ACTCCGTCTA ACTCGGAGAG GTTCACCATT 180

GATTCAAGCA CTATTGATTC TGAGACACTC ACTGGGTCTT TTCGAAACGA TATCGTTGAT 240

GATCCTTCTT TCTTGAATAG ACACAACAGT AAAGGTTTGG CGGAAACTAC GTTTAAGGCA 300

ATCTCAGGTG CTTCGGTTAG TGCCAATGTT TCCACGGCTA GGACTGGGAA TCAAATGGCA 360

TTGTGTTCAA GTGACGTTTT GGAGCCTGCT GCTTCATTTG AGAGCACTTC CTCGTTTGCT 420

TCTATTCCTT TGCAGCCGCT CCCTCGTGGT GGTTCGGGAC CCTTAAACGG ATTCATGTCC 480

GGGCCTCTAG AGAGAGGTTT TGCATCTGGT CCTTTGGATA GAAACAACGG TTTCATGTCT 540

GGGCCTATTG AAAAAGGAGT AATGTCTGGA CCCCTTGATG TATCTGATAG ATCTAATTTC 600

TCTGCGCCTC TTTCTTTTAG ACGTAAAAAG CCTCGGTTTC AGCGTTTTAT GAGGAGTGTG 660

AGCGGACCAA TGAAAAGTAC ATTAGCAAGG ACATTTTCTA GACGATCTGG AGGGTTAAGT 720

TGGATGCATC GCTTCTTCTT GCATCCAGAG ACTAGGGTTT CCTGGGCTGT TGGAAAGGAC 780

GGTAAGCTAC ATGGTGAAGA CCCTGAAAGT TGTCTAGAGA GCAACCGTAA CTTGCAATGG 840

GCTCATGGGA AAGCTGGAGA AGATAGGGTT CACGTTGTGC TTTCGGAGGA ACAAGGATGG 900

CTCTTTATCG GGATATATGA TGGGTTTAGT GGACCGGATG CTCCAGATTT CGTAATGAGT 960

CATCTTTATA AAGCTATTGA CAAGGAATTG GAAGGTCTTC TTTGGGATTA TGAAGAGCCA 1020

TCTGAAGATA ATCAATTGCA GCCTGACCAG GAACCTCCTA CAGAAGAGAA CATGTGTGAT 1080

CCAGAATCTA TCAGTGAGCA GCATTCAAAG TCAGTAGTGG CAGAAAGTGA GGAGGTTATG 1140

ATTGATGATA TCAGTAGCCT TGGAAATACC GATACTCAGA TTGCTGATGG TCCACCTGGA 1200

GACTCAGCTG GTCCTGGCAA GAAAAGCATG AGACTTTACG AGCTACTTCA ATTGGAACAG 1260

TGGGAAGGAG AAGAAATCGG GCTTAAACGA TATGGAGGGA ATGTCGCTCT AAACAATATG 1320

ACCAATCAGG TTGAAAATCC ATCTACTTCA GGTGGAGGAG CTGGAAATGA TCCTTGTACC 1380

ACCGACCGTA GTGCTCTTGA TGGGATTCCG AACTCGGGAC AAAGGCATGG GACTAAAAAA 1440

TCACAGATAA GCTCTAAGAT AAGAAGAATG TATCAAAAAC AGAAGTCTTT GCGGAAAAAA 1500

CTGTTTCCAT GGAGTTATGA TTGGCACAGG GAAGAAGGGA TTTGCGTTGA AGAGAAGATA 1560

GTGGAGTCAT CGGGACCGAT TAGGAGACGC TGGTCAGGGA CTGTGGACCA TGATGCTGTT 1620

CTAAGAGCAA TGGCTAGAGC ACTAGAGAGT ACTGAAGAGG CGTACATGGA TATGGTAGAG 1680

AAGTCTCTTG ACATAAACCC AGAGCTCGCG CTAATGGGTT CATGTGTTCT TGTAATGCTA 1740

ATGAAAGATC AAGATGTTTA CGTGATGAAC GTTGGGGATA GTCGGGCTAT CTTAGCCCAA 1800

GAAAGGCTCC ATGATCGTCA CTCTAATCCT GGTTTTGGGA ATGATGAGGG TATCGGGCAT 1860

AAGAGTAGGT CTCGAGAATC ACTTGTGCGT ATTGAACTGG ATAGAATATC AGAGGAATCT 1920

CCAATACACA ATCAAGCAAC TCCAATCAGT GTGTCAAACA AAAACAGAGA TGTGACCTCT 1980

TACCGGTTAA AGATGAGAGC AGTTCAACTA TCAAGTGACC ATAGCACAAG TGTGGAAGAG 2040

GAAATTTGGC GGATTAGATC TGAACATCCG GAAGATGACC AGTCGATACT TAAAGATAGA 2100

GTCAAAGGCC AACTAAAAGT CACTCGAGCT TTCGGTGCTG GATTTCTCAA AAAGCCAAAT 2160

TTCAATGAAG CTTTGCTTGA GATGTTCCAA GTAGAGTACA TTGGAACAGA CCCGTACATC 2220

ACATGCGAAC CGTGTACCGT CCATCACAGA CTGACTTCAA GCGATCGTTT CATGGTTTTA 2280

TCCTCGGATG GATTGTATGA ATACTTCAGC AACGAAGAGG TTGTTGCTCA CGTGACTTGG 2340

TTCATCGAAA ACGTTCCTGA AGGCGATCCT GCTCAATACC TCATTGCAGA GCTTCTCTCT 2400

CGTGCTGCCA CCAAGAACGG AATGGAGTTT CATGATCTGT TGGATATTCC TCAAGGAGAT 2460

AGAAGGAAGT ACCATGATGA TGTCTCTGTC ATGGTTGTGT CACTTGAAGG AAGGATTTGG 2520

CGCTCGTCTG GACAATATTA TCCAGAGAGA AAACAAAAAT TCAATAGATA A 2571

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdrlaffgvyD.Ghggsevakfcseklheila  62

         g+v++n+++n++e+++ts+++++++p+++dr+a++g+++ G+++ ++++++s+k++++++

Q: 433   GNVALNNMTNQVENPSTSGGGAGNDPCTTDRSALDGIPNsGQRHGTKKSQISSKIRRMYQ  492

         899*********************************************************

S: 63    eele..........................sseseerkvk.........kalakaFlstd  87

         ++++                          ss++ +r+++         +a+a+a++st+

Q: 493   KQKSlrkklfpwsydwhreegicveekiveSSGPIRRRWSgtvdhdavlRAMARALESTE  552

         ******************************9999999999999999999***********

S: 88    eelkvleeksldidk....sGstavvalikdsklyvanvGdSravLcrng.ka.......  135

         e++++++eksldi++    +Gs+++v+l+kd+++yv+nvGdSra+L++++ +

Q: 553   EAYMDMVEKSLDINPelalMGSCVLVMLMKDQDVYVMNVGDSRAILAQERlHDrhsnpgf  612

         *************************************************97735567799

S: 136   .......................................................velss  140

                                                                v+lss

Q: 613   gndegighksrsreslvrieldriseespihnqatpisvsnknrdvtsyrlkmraVQLSS  672

         99**********************************************************

S: 141   dHkpsredEleRieeag...gsvilkdgaRvlGvLavsRalGdlylk.............  184

         dH++s+e+E++Ri++++   +++ilkd  Rv+G+L+v+Ra+G+++lk

Q: 673   DHSTSVEEEIWRIRSEHpedDQSILKD--RVKGQLKVTRAFGAGFLKkpnfneallemfq  730

         *****************99999****9..*******************************

S: 185   .......pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekkeaeqe  237

                py+t+eP++++hrlts+d+f++L+sDGl++++snee+v++v++++e +++e++

Q: 731   veyigtdPYITCEPCTVHHRLTSSDRFMVLSSDGLYEYFSNEEVVAHVTWFIE-NVPEGD  789

         *****************************************************.******

S: 238   aakkLvklalargskdnv  255

         +a++L++++l+r++++n+

Q: 790   PAQYLIAELLSRAATKNG  807

         ****************98

Domain Sequence
(FASTA)

GNVALNNMTN QVENPSTSGG GAGNDPCTTD RSALDGIPNS GQRHGTKKSQ ISSKIRRMYQ 60

KQKSLRKKLF PWSYDWHREE GICVEEKIVE SSGPIRRRWS GTVDHDAVLR AMARALESTE 120

EAYMDMVEKS LDINPELALM GSCVLVMLMK DQDVYVMNVG DSRAILAQER LHDRHSNPGF 180

GNDEGIGHKS RSRESLVRIE LDRISEESPI HNQATPISVS NKNRDVTSYR LKMRAVQLSS 240

DHSTSVEEEI WRIRSEHPED DQSILKDRVK GQLKVTRAFG AGFLKKPNFN EALLEMFQVE 300

YIGTDPYITC EPCTVHHRLT SSDRFMVLSS DGLYEYFSNE EVVAHVTWFI ENVPEGDPAQ 360

YLIAELLSRA ATKNG 375

Keyword

Complete proteome; Developmental protein; Hydrolase; Magnesium; Manganese; Metal-binding; Nucleus; Phosphoprotein; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Brassica rapa"; ?>Glycine max"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Setaria italica"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0046872	; F:metal ion binding
GO:0005543	; F:phospholipid binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0010074	; P:maintenance of meristem identity
GO:0009934	; P:regulation of meristem structural organization
GO:0006355	; P:regulation of transcription, DNA-dependent

KEGG

ath:AT2G46920

;

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 2.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

PS01032

; PP2C; FALSE_NEG.

Prints

Created Date

20-Feb-2013