| Tag | Content |
|---|
| EKPD ID | EKS-ART-00939 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| Atypical/PDHK | 148.8 | 1.6E-43 | 227 | 354 | 128 |
|
| Status | Reviewed |
| Ensembl Protein | AT3G06483.1 |
| UniProt Accession | Q9SBJ1; O82657; Q9C8Z0; Q9SQV2; |
| Protein Name | [Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial |
| Protein Synonyms/Alias | AtPDHK; Pyruvate dehydrogenase kinase; |
| Gene Name | PDK |
| Gene Synonyms/Alias | PDK; PDHK, YA5; At3g06483; F24P17.1, F5E6.19; |
| Ensembl Information | |
| Organism | Arabidopsis thaliana |
| Functional Description | Serine protein kinase that inhibits the mitochondrialpyruvate dehydrogenase (PDH) complex (mtPDC) by phosphorylation of the E1 alpha subunit on Ser residues, thus contributing to the regulation of glucose metabolism. |
| Protein Length | 366 |
Protein Sequence
(FASTA) | | MAVKKACEMF PKSLIEDVHK WGCMKQTGVS LRYMMEFGSK PTERNLLISA QFLHKELPIR 60 | | VARRAIELQT LPYGLSDKPA VLKVRDWYLE SFRDMRAFPE IKDSGDEKDF TQMIKAVKVR 120 | | HNNVVPMMAL GVNQLKKGMN SGNLDEIHQF LDRFYLSRIG IRMLIGQHVE LHNPNPPLHT 180 | | VGYIHTKMSP MEVARNASED ARSICFREYG SAPEINIYGD PSFTFPYVPT HLHLMMYELV 240 | | KNSLRAVQER FVDSDRVAPP IRIIVADGIE DVTIKVSDEG GGIARSGLPR IFTYLYSTAR 300 | | NPLEEDVDLG IADVPVTMAG YGYGLPISRL YARYFGGDLQ IISMEGYGTD AYLHLSRLGD 360 | | SQEPLP 366 |
|
Nucleotide Sequence
(FASTA) | | ATGGCAGTGA AGAAAGCCTG CGAAATGTTC CCGAAGAGTT TGATCGAAGA TGTTCACAAA 60 | | TGGGGTTGCA TGAAGCAAAC CGGTGTTAGC CTTAGATACA TGATGGAGTT TGGTTCCAAA 120 | | CCTACTGAGA GGAATCTTTT GATTTCTGCT CAGTTTTTGC ATAAGGAGCT TCCGATTCGC 180 | | GTCGCCAGGA GAGCGATCGA ACTCCAGACG CTTCCTTATG GTCTCTCTGA TAAACCTGCC 240 | | GTTTTGAAGG TGCGGGATTG GTATTTGGAA TCTTTCAGGG ACATGAGAGC ATTTCCTGAG 300 | | ATTAAGGATT CGGGTGACGA GAAAGATTTC ACTCAGATGA TTAAGGCTGT CAAAGTAAGG 360 | | CATAACAATG TGGTTCCCAT GATGGCTTTG GGTGTTAATC AGCTCAAGAA AGGAATGAAT 420 | | TCTGGAAATC TTGATGAGAT TCATCAGTTT CTTGATCGTT TCTACTTGTC GCGAATCGGG 480 | | ATCCGGATGC TTATTGGGCA GCACGTTGAG TTGCATAATC CAAATCCACC GCTTCATACA 540 | | GTGGGTTATA TACACACAAA GATGTCTCCT ATGGAGGTAG CAAGGAATGC AAGTGAAGAT 600 | | GCTCGGTCAA TTTGTTTCCG AGAGTACGGT TCTGCACCGG AAATAAACAT ATATGGCGAT 660 | | CCCAGTTTCA CCTTTCCGTA TGTTCCAACG CATTTGCATC TTATGATGTA TGAGCTAGTC 720 | | AAGAACTCTC TACGTGCTGT CCAAGAGCGA TTTGTTGACT CTGATAGAGT TGCACCACCA 780 | | ATCCGCATTA TAGTTGCTGA TGGAATCGAA GATGTTACTA TAAAGGTCTC AGATGAAGGT 840 | | GGAGGTATAG CAAGAAGCGG TCTTCCCAGA ATATTCACCT ATCTTTACAG CACTGCAAGA 900 | | AACCCGCTTG AGGAGGATGT CGATTTAGGA ATAGCTGATG TTCCCGTGAC TATGGCTGGA 960 | | TATGGTTATG GTCTTCCAAT TAGTCGCTTG TATGCTCGAT ATTTCGGTGG AGATTTGCAG 1020 | | ATCATATCCA TGGAAGGATA TGGGACTGAT GCATACTTGC ACTTGTCTCG CCTTGGAGAT 1080 | | TCGCAAGAGC CTTTACCCTG A 1101 |
|
| Domain Profile | S: 1 yvpshlyyllfellknamratveshedkkv.lpdvkvlvalgkedliikisdrGGGvplr 59 | yvp+hl+ +++el+kn++ra+ e++ d++ p+++++va g ed++ik+sd+GGG++++ | Q: 227 YVPTHLHLMMYELVKNSLRAVQERFVDSDRvAPPIRIIVADGIEDVTIKVSDEGGGIARS 286 | 9***********************998887689*************************** |
| S: 60 kidrlldymystapapskdd......araaplaGfGyGlpisrlyakylqGdlkllsleG 113 | + r++ y ysta +p ++d + +aG+GyGlpisrlya+y++Gdl++ s+eG | Q: 287 GLPRIFTYLYSTARNPLEEDvdlgiaDVPVTMAGYGYGLPISRLYARYFGGDLQIISMEG 346 | ******************99888865455679**************************** |
| S: 114 iGtdaviylk 123 | +Gtda yl+ | Q: 347 YGTDA--YLH 354 | *****..554 |
|
Domain Sequence
(FASTA) | | YVPTHLHLMM YELVKNSLRA VQERFVDSDR VAPPIRIIVA DGIEDVTIKV SDEGGGIARS 60 | | GLPRIFTYLY STARNPLEED VDLGIADVPV TMAGYGYGLP ISRLYARYFG GDLQIISMEG 120 | | YGTDAYLH 128 |
|
| Keyword | ATP-binding; Complete proteome; Kinase; Mitochondrion; Nucleotide-binding; Phosphoprotein; Pyruvate; Reference proteome; Serine/threonine-protein kinase; Transferase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |