EKS-ART-00007

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ART-00007

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	292.9	4.6E-87	23	274	252

Status

Unreviewed

Ensembl Protein

AT3G13530.1

UniProt Accession

O81809;

Protein Name

Protein Synonyms/Alias

MAP3K epsilon protein kinase;

Gene Name

MAP3K epsilon

Gene Synonyms/Alias

MAP3K epsilon;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
AT3G13530	AT3G13530.1	AT3G13530.1

Organism

Arabidopsis thaliana

Functional Description

Protein Length

1368

Protein Sequence
(FASTA)

MARQMTSSQF HKSKTLDNKY MLGDEIGKGA YGRVYKGLDL ENGDFVAIKQ VSLENIVQED 60

LNTIMQEIDL LKNLNHKNIV KYLGSSKTKT HLHIILEYVE NGSLANIIKP NKFGPFPESL 120

VAVYIAQVLE GLVYLHEQGV IHRDIKGANI LTTKEGLVKL ADFGVATKLN EADVNTHSVV 180

GTPYWMAPEV IEMSGVCAAS DIWSVGCTVI ELLTCVPPYY DLQPMPALFR IVQDDNPPIP 240

DSLSPDITDF LRQCFKKDSR QRPDAKTLLS HPWIRNSRRA LQSSLRHSGT IKYMKEATAS 300

SEKDDEGSQD AAESLSGENV GISKTDSKSK LPLVGVSSFR SEKDQSTPSD LGEEGTDNSE 360

DDIMSDQVPT LSIHEKSSDA KGTPQDVSDF HGKSERGETP ENLVTETSEA RKNTSAIKHV 420

GKELSIPVDQ TSHSFGRKGE ERGIRKAVKT PSSVSGNELA RFSDPPGDAS LHDLFHPLDK 480

VSEGKPNEAS TSMPTSNVNQ GDSPVADGGK NDLATKLRAT IAQKQMEGET GHSNDGGDLF 540

RLMMGVLKDD VIDIDGLVFD EKVPAENLFP LQAVEFSRLV SSLRPDESED AIVSSCQKLV 600

AMFRQRPEQK VVFVTQHGFL PLMDLLDIPK SRVICAVLQL INEIIKDNTD FQENACLVGL 660

IPVVMSFAGP ERDRSREIRK EAAYFLQQLC QSSPLTLQMF IACRGIPVLV GFLEADYAKY 720

REMVHLAIDG MWQVFKLKRS TPRNDFCRIA AKNGILLRLI NTLYSLNEAT RLASISGGLD 780

GQAPRVRSGQ LDPNNPIFGQ NETSSLSMID QPDVLKTRHG GGEEPSHAST SNSQRSDVHQ 840

PDALHPDGDK PRVSSVAPDA STSGTEDVRQ QHRISLSANR TSTDKLQKLA EGASNGFPVT 900

QTEQVRPLLS LLDKEPPSRH YSGQLDYVKH ITGIERHESR LPLLHGSNEK KNNGDLDFLM 960

AEFAEVSGRG KENGSLDTTT RYPSKTMTKK VLAIEGVAST SGIASQTASG VLSGSGVLNA 1020

RPGSATSSGL LAHMVSTLSA DVAREYLEKV ADLLLEFARA DTTVKSYMCS QSLLSRLFQM 1080

FNRVEPPILL KILECTNHLS TDPNCLENLQ RADAIKHLIP NLELKDGHLV YQIHHEVLSA 1140

LFNLCKINKR RQEQAAENGI IPHLMLFIMS DSPLKQYALP LLCDMAHASR NSREQLRAHG 1200

GLDVYLSLLD DEYWSVIALD SIAVCLAQDN DNRKVEQALL KQDAIQKLVD FFQSCPERHF 1260

VHILEPFLKI ITKSYRINKT LAVNGLTPLL ISRLDHQDAI ARLNLLKLIK AVYEHHPRPK 1320

QLIVENDLPQ KLQNLIEERR DGQRSGGQVL VKQMATSLLK ALHINTIL 1368

Nucleotide Sequence
(FASTA)

ATGGCGCGGC AAATGACGTC ATCTCAGTTT CACAAATCAA AGACTCTCGA CAACAAATAT 60

ATGCTGGGAG ATGAAATTGG TAAAGGAGCT TATGGTCGAG TTTATAAAGG ATTAGACTTG 120

GAGAATGGTG ACTTTGTGGC CATTAAACAA GTCTCTTTGG AAAATATTGT TCAAGAGGAT 180

CTTAACACCA TTATGCAAGA AATTGATCTT TTGAAGAACT TGAACCATAA AAACATTGTG 240

AAGTATCTTG GGTCGTCGAA GACAAAGACT CACCTTCACA TTATTTTGGA GTACGTTGAG 300

AATGGCTCTC TTGCAAACAT TATTAAACCA AATAAATTTG GACCTTTCCC AGAATCTTTG 360

GTGGCTGTTT ACATTGCTCA GGTCTTGGAA GGTTTGGTAT ATCTGCATGA GCAGGGTGTT 420

ATACACCGTG ATATTAAGGG TGCAAATATT TTGACGACAA AGGAGGGTCT TGTGAAGCTT 480

GCTGACTTTG GAGTTGCCAC TAAACTTAAC GAGGCTGATG TTAATACTCA CTCGGTGGTT 540

GGAACTCCTT ACTGGATGGC TCCTGAGGTT ATTGAAATGT CAGGAGTTTG TGCTGCTTCT 600

GACATTTGGA GCGTTGGATG CACTGTTATC GAACTTCTGA CATGTGTACC TCCTTACTAT 660

GATCTGCAAC CCATGCCAGC CCTCTTTCGT ATTGTTCAGG ATGACAACCC TCCTATTCCT 720

GATAGTCTTT CTCCAGATAT TACGGACTTT CTACGACAGT GCTTCAAGAA GGATTCCAGG 780

CAGAGGCCTG ATGCAAAGAC ACTGCTCTCT CACCCTTGGA TACGAAACTC TAGACGAGCT 840

TTGCAGTCAT CACTTCGGCA TAGTGGCACC ATCAAATATA TGAAGGAAGC CACTGCAAGT 900

TCAGAGAAGG ATGATGAAGG TAGTCAAGAT GCAGCAGAAA GCCTTTCAGG AGAAAATGTG 960

GGAATATCAA AAACTGACTC GAAAAGCAAA TTACCTCTGG TAGGGGTGTC GAGTTTTAGG 1020

TCTGAGAAAG ATCAGTCGAC ACCCAGTGAT CTTGGTGAAG AAGGAACAGA TAATTCAGAA 1080

GATGATATTA TGTCAGATCA AGTTCCTACA CTGTCGATCC ATGAGAAATC TTCGGATGCT 1140

AAGGGGACAC CTCAAGATGT ATCAGACTTT CATGGGAAAT CTGAACGTGG TGAAACACCT 1200

GAAAATCTTG TAACGGAAAC TTCTGAAGCT AGAAAAAATA CTTCAGCAAT AAAGCACGTT 1260

GGCAAAGAAT TATCCATCCC AGTGGACCAG ACATCACATA GTTTTGGCCG CAAAGGTGAA 1320

GAACGTGGGA TTCGAAAGGC TGTGAAGACT CCATCTAGTG TTAGTGGGAA TGAACTGGCT 1380

AGGTTTAGTG ATCCTCCTGG GGATGCTTCT TTGCATGATT TATTTCACCC ATTGGATAAA 1440

GTGTCTGAGG GAAAACCAAA TGAAGCCTCA ACATCCATGC CTACGTCAAA TGTCAACCAA 1500

GGTGATTCTC CTGTTGCAGA TGGTGGAAAG AATGATCTGG CTACAAAATT GAGGGCTACA 1560

ATTGCTCAGA AGCAAATGGA GGGGGAAACA GGGCACTCAA ATGATGGTGG TGATCTTTTT 1620

CGCTTGATGA TGGGTGTTTT GAAAGATGAT GTTATTGACA TTGATGGCTT GGTATTTGAT 1680

GAAAAAGTGC CCGCGGAGAA TCTTTTTCCT CTGCAGGCAG TCGAGTTCAG CAGACTGGTC 1740

AGCTCCTTGA GGCCAGATGA GTCAGAAGAT GCAATAGTAT CTTCTTGTCA GAAACTTGTT 1800

GCCATGTTTC GTCAGAGACC TGAGCAGAAA GTAGTATTTG TGACACAGCA TGGTTTCCTG 1860

CCTCTAATGG ATCTACTCGA TATTCCTAAA TCTCGAGTAA TATGTGCTGT GCTGCAGCTG 1920

ATAAACGAAA TTATTAAAGA TAACACTGAC TTCCAGGAAA ATGCTTGTCT TGTTGGCCTT 1980

ATTCCTGTTG TAATGAGTTT TGCTGGTCCT GAGAGGGATC GTTCTCGCGA AATTCGTAAA 2040

GAAGCAGCTT ACTTCTTGCA GCAGCTTTGT CAGTCAAGCC CCTTGACGTT GCAAATGTTC 2100

ATAGCTTGCC GTGGAATACC CGTTTTGGTG GGATTTCTTG AAGCAGATTA TGCCAAATAC 2160

AGGGAGATGG TTCACTTGGC TATTGATGGG ATGTGGCAGG TATTTAAACT CAAAAGATCC 2220

ACCCCAAGAA ATGATTTCTG CCGTATAGCT GCAAAGAATG GAATTCTTCT GAGGCTAATC 2280

AACACTCTTT ATAGCTTGAA TGAGGCAACC CGGCTGGCTT CTATATCAGG GGGCCTGGAT 2340

GGTCAAGCTC CACGAGTGCG CTCTGGTCAA CTTGACCCTA ACAATCCTAT TTTTGGTCAA 2400

AATGAGACTT CTTCACTCAG TATGATTGAT CAGCCTGATG TATTGAAAAC TAGGCATGGG 2460

GGTGGTGAAG AGCCTTCTCA TGCTTCAACC TCAAATTCTC AAAGATCAGA TGTCCATCAA 2520

CCAGATGCTT TGCACCCAGA TGGTGATAAG CCTAGAGTAA GCAGTGTTGC ACCAGATGCC 2580

TCAACCTCTG GCACAGAAGA TGTTAGACAA CAGCATCGAA TATCTCTTTC CGCCAATAGG 2640

ACATCGACAG ATAAGCTTCA GAAGCTGGCA GAGGGCGCCT CTAATGGTTT TCCTGTTACT 2700

CAGACAGAAC AAGTTCGACC TTTGCTTAGC TTGTTGGATA AAGAACCCCC TTCAAGACAT 2760

TATTCTGGTC AACTGGATTA TGTTAAGCAT ATCACTGGCA TAGAGAGACA TGAAAGTAGA 2820

CTTCCTCTTT TGCATGGATC AAATGAAAAG AAAAACAACG GAGACCTAGA TTTTCTGATG 2880

GCTGAATTTG CAGAGGTCTC TGGACGTGGA AAGGAAAATG GAAGTCTTGA TACTACGACT 2940

AGATATCCCA GTAAAACAAT GACAAAGAAG GTTCTGGCTA TTGAAGGAGT TGCTTCAACA 3000

TCTGGGATTG CATCTCAGAC AGCATCTGGA GTACTGTCAG GTTCGGGTGT TCTAAACGCT 3060

AGACCTGGAA GTGCCACATC ATCTGGTTTA CTTGCCCATA TGGTCTCTAC GCTGAGTGCA 3120

GATGTTGCAA GGGAATACTT GGAGAAAGTT GCTGACCTGC TTCTTGAATT TGCTCGAGCT 3180

GATACGACAG TAAAGTCATA TATGTGCAGC CAAAGCTTAC TCAGTCGTCT TTTTCAGATG 3240

TTCAACCGTG TAGAACCTCC TATTCTGTTA AAGATACTGG AGTGCACAAA TCATTTATCA 3300

ACTGATCCAA ATTGCTTGGA GAATCTGCAG CGTGCAGATG CAATTAAGCA TTTGATCCCC 3360

AACCTTGAGC TTAAGGATGG GCATCTTGTT TATCAGATCC ATCATGAGGT GCTTAGTGCA 3420

CTATTCAACC TGTGCAAGAT AAACAAGAGG AGGCAGGAAC AAGCGGCTGA AAACGGAATC 3480

ATTCCGCATC TGATGCTTTT CATTATGTCA GATTCTCCTC TGAAACAGTA TGCATTGCCA 3540

CTACTCTGCG ATATGGCTCA TGCATCTCGA AATTCAAGAG AACAGTTAAG GGCCCACGGT 3600

GGTCTTGATG TTTACCTGAG TTTACTCGAT GATGAATACT GGTCCGTGAT AGCCTTAGAT 3660

TCAATCGCTG TTTGCTTGGC GCAAGACAAT GACAACCGCA AGGTAGAGCA GGCATTGCTC 3720

AAGCAAGATG CAATTCAGAA ATTAGTTGAC TTCTTCCAGA GCTGCCCAGA GAGACACTTC 3780

GTGCACATAT TGGAGCCATT CTTAAAGATT ATCACGAAAT CATATCGGAT CAATAAGACA 3840

TTAGCTGTAA ATGGATTGAC TCCACTGCTT ATTTCAAGGC TAGACCATCA AGATGCGATT 3900

GCTCGACTTA ACCTCCTAAA ACTCATCAAG GCTGTTTATG AACATCATCC ACGGCCGAAA 3960

CAGCTGATCG TAGAGAACGA CCTTCCTCAA AAACTGCAGA ATCTAATAGA AGAACGACGA 4020

GATGGACAAC GTTCAGGAGG CCAAGTTCTG GTGAAACAAA TGGCAACATC TCTCCTCAAA 4080

GCACTTCACA TCAACACAAT ATTGTGA 4107

Domain Profile

S: 4     revigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkHeni  63

         ++ igkG++g+vy++ld+++g  +a+K+v++   ++  ++ ++++++Ei+llk+l+H+ni

Q: 23    GDEIGKGAYGRVYKGLDLENGDFVAIKQVSL---ENIVQEDLNTIMQEIDLLKNLNHKNI  79

         678**************************98...3455679*******************

S: 64    vkyyGveveeeelkiflEyvegGslsslle..kygkleesvikkytkqileglayLHekk  121

         vky+G+++ +++l+i+lEyve+Gsl+++++  k+g++ es++ +y  q+legl yLHe++

Q: 80    VKYLGSSKTKTHLHIILEYVENGSLANIIKpnKFGPFPESLVAVYIAQVLEGLVYLHEQG  139

         *****************************9989***************************

S: 122   ivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikkkek  181

         ++HRDiKgaNil +++g+vkl+DFG++++l+e+  +   ++s++Gt+++maPEvi+ +

Q: 140   VIHRDIKGANILTTKEGLVKLADFGVATKLNEADVN---THSVVGTPYWMAPEVIEMS--  194

         *******************************99877...89**************887..

S: 182   gygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkdfle  241

         g  +++DiWs+gc+vie+lt  +P+ +l +++ ++f++ ++  +P+ip++ls++  dfl+

Q: 195   GVCAASDIWSVGCTVIELLTCVPPYYDL-QPMPALFRIVQDD-NPPIPDSLSPDITDFLR  252

         9***************************.9*********999.*****************

S: 242   kcleldpkkrpsaeeLLkhefl  263

         +c+++d ++rp a+ LL+h+++

Q: 253   QCFKKDSRQRPDAKTLLSHPWI  274

         ********************96

Domain Sequence
(FASTA)

GDEIGKGAYG RVYKGLDLEN GDFVAIKQVS LENIVQEDLN TIMQEIDLLK NLNHKNIVKY 60

LGSSKTKTHL HIILEYVENG SLANIIKPNK FGPFPESLVA VYIAQVLEGL VYLHEQGVIH 120

RDIKGANILT TKEGLVKLAD FGVATKLNEA DVNTHSVVGT PYWMAPEVIE MSGVCAASDI 180

WSVGCTVIEL LTCVPPYYDL QPMPALFRIV QDDNPPIPDS LSPDITDFLR QCFKKDSRQR 240

PDAKTLLSHP WI 252

Keyword

Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Cyanidioschyzon merolae"; ?>Glycine max"; ?>Musa acuminata"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Physcomitrella patens"; ?>Populus trichocarpa"; ?>Selaginella moellendorffii"; ?>Setaria italica"; ?>Solanum lycopersicum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR000225	; Armadillo.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00185	; ARM; 3.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013