EKS-ART-00476

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ART-00476

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	298.5	6.0E-89	12	266	255

Status

Reviewed

Ensembl Protein

AT5G58380.1

UniProt Accession

Q9C562; Q9LVL3;

Protein Name

CBL-interacting serine/threonine-protein kinase 10

Protein Synonyms/Alias

SNF1-related kinase 3.8; SOS2-like protein kinase PKS2; SOS3-interacting protein 1;

Gene Name

CIPK10

Gene Synonyms/Alias

CIPK10; PKS2, SIP1, SnRK3.8; At5g58380; MCK7.25;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
AT5G58380	AT5G58380.1	AT5G58380.1

Organism

Arabidopsis thaliana

Functional Description

CIPK serine-threonine protein kinases interact with CBLproteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium- dependent manner (By similarity).

Protein Length

479

Protein Sequence
(FASTA)

MENKPSVLTD KYDVGRLLGQ GTFAKVYYGR SILTNQSVAI KMIDKEKVMK VGLIEQIKRE 60

ISVMRIARHP NVVELYEVMA TKTRIYFVME YCKGGELFNK VAKGKLRDDV AWKYFYQLIN 120

AVDFCHSREV YHRDIKPENL LLDDNENLKV SDFGLSALAD CKRQDGLLHT TCGTPAYVAP 180

EVINRKGYDG TKADIWSCGV VLFVLLAGYL PFHDSNLMEM YRKIGKADFK APSWFAPEVR 240

RLLCKMLDPN PETRITIARI RESSWFRKGL HMKQKKMEKR VKEINSVEAG TAGTNENGAG 300

PSENGAGPSE NGDRVTEENH TDEPTNLNAF DLIALSAGFD LAGLFGDDNK RESRFTSQKP 360

ASVIISKLEE VAQRLKLSIR KREAGLFKLE RLKEGRKGIL SMDAEIFQVT PNFHLVEVKK 420

SNGDTLEYQK LVAEDLRPAL SDIVWVWQGE KDELTSQQET EYQQQQQQEQ QEQEEPLKF 479

Nucleotide Sequence
(FASTA)

ATGGAAAATA AGCCAAGTGT TTTGACTGAT AAATATGATG TTGGGAGGTT ATTGGGTCAA 60

GGTACTTTTG CCAAGGTGTA TTATGGAAGG AGTATTCTTA CTAACCAGAG TGTTGCTATC 120

AAGATGATCG ATAAGGAAAA GGTTATGAAA GTTGGGCTTA TCGAACAGAT CAAGAGAGAG 180

ATCTCTGTTA TGAGGATTGC TAGACACCCT AACGTTGTGG AGCTATATGA GGTCATGGCA 240

ACAAAAACGA GGATCTACTT TGTTATGGAG TATTGTAAAG GTGGAGAGCT TTTCAACAAG 300

GTTGCCAAAG GGAAATTGAG AGATGATGTT GCTTGGAAAT ACTTTTATCA GCTTATCAAC 360

GCAGTTGATT TTTGCCACAG CCGAGAGGTG TATCATCGTG ACATAAAGCC GGAGAACCTA 420

TTGCTAGATG ATAATGAGAA TCTCAAGGTA TCTGATTTCG GGTTAAGCGC CCTTGCTGAC 480

TGCAAGAGAC AAGATGGCCT CCTCCACACT ACTTGTGGTA CACCTGCATA TGTTGCTCCA 540

GAAGTGATCA ATCGAAAAGG CTATGATGGC ACAAAAGCAG ATATTTGGTC TTGTGGTGTG 600

GTTTTGTTTG TCCTATTGGC AGGCTATCTA CCTTTCCATG ACTCCAATCT GATGGAGATG 660

TACAGGAAGA TAGGAAAAGC AGATTTTAAG GCACCAAGCT GGTTTGCTCC AGAAGTACGG 720

AGGCTGTTGT GTAAGATGCT AGACCCTAAC CCTGAAACTA GAATCACCAT CGCAAGAATC 780

AGGGAGAGTT CTTGGTTCAG AAAAGGTTTA CATATGAAAC AGAAAAAGAT GGAGAAACGA 840

GTCAAAGAGA TAAACTCTGT GGAAGCTGGT ACTGCAGGTA CAAATGAGAA CGGAGCAGGT 900

CCAAGTGAGA ATGGAGCAGG TCCAAGTGAA AACGGAGACA GGGTCACGGA GGAAAACCAT 960

ACAGACGAAC CTACAAATTT GAACGCTTTT GATTTAATTG CCTTGTCTGC TGGGTTTGAT 1020

CTGGCAGGAC TGTTTGGAGA TGATAACAAG AGAGAATCTA GATTCACATC ACAGAAACCT 1080

GCTTCAGTGA TCATATCTAA GCTGGAGGAA GTAGCACAGC GATTGAAACT GAGCATAAGA 1140

AAGCGAGAAG CAGGTTTGTT CAAATTGGAA CGATTAAAAG AAGGAAGAAA AGGGATTCTG 1200

TCGATGGATG CAGAAATATT TCAAGTGACG CCAAACTTTC ATTTAGTGGA AGTGAAGAAA 1260

TCAAATGGAG ATACTCTCGA GTATCAGAAA TTAGTAGCAG AGGATCTTAG ACCTGCTCTG 1320

TCAGATATTG TATGGGTTTG GCAGGGTGAG AAAGATGAGC TTACTTCACA GCAAGAGACA 1380

GAATACCAAC AACAACAACA ACAAGAACAA CAAGAACAGG AAGAACCATT GAAGTTTTGA 1440

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y++++ lG+g+f+kV   ++ +t+++va+K+i+k+k+ +   +e+ikrEi+++++ +hpn

Q: 12    YDVGRLLGQGTFAKVYYGRSILTNQSVAIKMIDKEKVmKVGLIEQIKREISVMRIARHPN  71

         8999******************************9985777899****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         +++l+ev+ tk+++y+v+ey++ggeLf+++ +kg+l+ + a k+f ql++av+++hs+++

Q: 72    VVELYEVMATKTRIYFVMEYCKGGELFNKV-AKGKLRDDVAWKYFYQLINAVDFCHSREV  130

         *****************************7.899**************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkeg...klletfcGsppYaaPellkgkkYeg  176

          HrD+KpeNllld++en+k++DFGl++l + +    ll+t+cG+p+Y+aPe++++k Y+g

Q: 131   YHRDIKPENLLLDDNENLKVSDFGLSALADCKrqdGLLHTTCGTPAYVAPEVINRKGYDG  190

         **************************96655444599***********************

S: 177   pkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvd  236

         +k+D+Ws+GvvL++l++g lPf+++nl e+++ki k +++ p++  +e+++Ll k+L  +

Q: 191   TKADIWSCGVVLFVLLAGYLPFHDSNLMEMYRKIGKADFKAPSWFAPEVRRLLCKMLDPN  250

         ************************************************************

S: 237   pekRatieeilkhewl  252

         pe+R+ti +i++++w+

Q: 251   PETRITIARIRESSWF  266

         ***************6

Domain Sequence
(FASTA)

YDVGRLLGQG TFAKVYYGRS ILTNQSVAIK MIDKEKVMKV GLIEQIKREI SVMRIARHPN 60

VVELYEVMAT KTRIYFVMEY CKGGELFNKV AKGKLRDDVA WKYFYQLINA VDFCHSREVY 120

HRDIKPENLL LDDNENLKVS DFGLSALADC KRQDGLLHTT CGTPAYVAPE VINRKGYDGT 180

KADIWSCGVV LFVLLAGYLP FHDSNLMEMY RKIGKADFKA PSWFAPEVRR LLCKMLDPNP 240

ETRITIARIR ESSWF 255

Keyword

ATP-binding; Complete proteome; Kinase; Manganese; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Arabidopsis lyrata"; ?>Brachypodium distachyon"; ?>Brassica rapa"; ?>Glycine max"; ?>Hordeum vulgare"; ?>Musa acuminata"; ?>Oryza brachyantha"; ?>Oryza glaberrima"; ?>Oryza indica"; ?>Oryza sativa"; ?>Populus trichocarpa"; ?>Setaria italica"; ?>Solanum lycopersicum"; ?>Solanum tuberosum"; ?>Sorghum bicolor"; ?>Vitis vinifera"; ?>Zea mays"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007165	; P:signal transduction

KEGG

ath:AT5G58380

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR018451	; NAF/FISL_domain.
IPR004041	; NAF_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF03822	; NAF; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50816	; NAF; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013