EKS-CAE-00219

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAE-00219

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	317.2	1.0E-94	58	309	252

Status

Unreviewed

Ensembl Protein

B0496.3a

UniProt Accession

H2KYA5;

Protein Name

Protein Synonyms/Alias

Protein UNC-82, isoform e;

Gene Name

unc-82

Gene Synonyms/Alias

unc-82;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
B0496.3	B0496.3e.2	B0496.3e.2
B0496.3	B0496.3e.1	B0496.3e.1
B0496.3	B0496.3f	B0496.3f
B0496.3	B0496.3g	B0496.3g
B0496.3	B0496.3h	B0496.3h
B0496.3	B0496.3d	B0496.3d
B0496.3	B0496.3b	B0496.3b
B0496.3	B0496.3c	B0496.3c
B0496.3	B0496.3a	B0496.3a

Organism

Caenorhabditis elegans

Functional Description

Protein Length

1483

Protein Sequence
(FASTA)

MPVGNSGSRS GRLARISQSN IRPFGSNGGG ATNSYGPGTH PMSGAEPCSP TKKEKHRFEI 60

TKKLGSGTYG KVSLAYDHKF DREVAVKLIK KSAIESKADL VRIRREIRIM SALNHPNIIQ 120

IYEVFENKDK IILVMEYSSG GELYDYVSRC GSLPEAEARR IFRQITSAVL YCHKHRVAHR 180

DLKLENILLD QNNNAKIADF GLSNYFADKN LLTTFCGSPL YASPEIINGT PYKGPEVDCW 240

SLGILLYTLV YGSMPFDGRD FNRMVRQIKR GAYFEPETPS TASMLIRNML RVNPERRATI 300

FDIASHWWLN LEENMPVIQE LPENQIIDHT PLTEREETMI VQDLADEQDV FMEFGHLSSE 360

TRRKIEDFRI RRKEAEEFND NSPVKPPKAR KTDELTGKIS KEQPEEMKSA EKSLRGVKEE 420

KEKPKVVDPN DPLERLRQIE NRLGQNKKDK EAAKTSARVE TVKLKEVKKE KSPEQQPEDP 480

KTARGTSKPA DSRAPSFVPV KDRPETSEPE RPRTRPHLTA SAYRIETDSL NMLMNQVLEQ 540

MEKGPVNLNI IARIKAHPLY DTRPMVKELL ESIIAAQPEP VQKQTSKVVE QQTFSRQNTL 600

TRKKKEDPLE EEIPEVPSPS RKMKERPWHS VEVGFDPDEE PEHDRMQESI ASNATEVTVQ 660

DTSFEDDSSD EEERKKTPVA STPKTPVLIV EKQESSTNAE DEESDEGDDY SDAEMEELAD 720

EVDKKGPSDS KLAPVVENLE ANPPPDPSSS PQFLDAFDRG LIKRQSKGKY QAKEILQTYP 780

NNKLDARGID VELRRKLRME KVKADLLKQP KDGDKPRNSY VGSVPPRSPP PIVVKSDGEE 840

LDDEEEEEED EEEIEETDSE EGSDFENFKP KRPIIAAVRR DDGAVVPVIH QTTRPAVVSP 900

NSQNPRYQVA SPKTSTVIQA TPEKVPVAGT SAKYLVTVAE LKLKPTDKKE EAQLKEQLKD 960

SEINSERKVT KGAAPSTISQ DSDGKDTFES ASAYIRRKNR ERRQRNRTIG TAEEALRALE 1020

RPSVDPYDDR AFSPLSTDPF YSHHSSGSAA PSALGYVRPR YHDDSYRTHR DSDYRPMSPT 1080

SRYTAAVTRD DRGKSTSYDP HETTRPSYDR GYITSSNASP SYTRKFEHEQ PTLNSWANDR 1140

KFEVYKTRAE RDAERNTYHP TGTTGASSYR PSSYYTSASD RPVTGLRRPE ESYTSSTNYG 1200

RYDGRSTTPS NDQYAISTAL AENQASSMNN RFRPTARRVA SAMTDADRRN YHRSRSMDRN 1260

KVDYEYGSNL LNRLTTPDSH GDYSYVNYHD SSNGRSNITL EKDGQPRSIL KNKQSADIEP 1320

RVESSYEPSN GVRSVASVGP HSRNIDSTSS ALDNPKKKRS LLSFNRRKTS EVRMGADGKL 1380

VTNGYDSTPS SRDFKRPSSP IDRIKSLFRK NESSGTGHSD YYNSSRNYTS SNPVSTTREP 1440

YVAQYRKYPG STSRDTSSAL NRYSYTPGLT DQRRHWYDDP NIY 1483

Nucleotide Sequence
(FASTA)

ATGCCCGTCG GAAATTCGGG ATCTCGATCG GGTCGATTGG CACGTATCAG TCAATCGAAT 60

ATACGACCGT TTGGATCAAA TGGCGGTGGA GCTACGAACA GTTATGGACC CGGAACCCAT 120

CCAATGTCCG GTGCTGAACC ATGTAGCCCA ACAAAAAAGG AAAAGCATCG ATTCGAAATC 180

ACAAAAAAAC TTGGCTCCGG AACATACGGA AAAGTATCGT TGGCATATGA TCACAAGTTC 240

GATCGAGAGG TTGCTGTCAA ATTGATCAAA AAAAGCGCAA TTGAAAGCAA AGCTGACTTG 300

GTTCGAATTC GAAGGGAAAT TCGTATTATG AGTGCATTAA ACCATCCAAA TATTATTCAG 360

ATTTATGAAG TGTTTGAAAA CAAAGATAAA ATTATTCTCG TAATGGAGTA CTCTAGCGGT 420

GGAGAATTGT ATGATTATGT CTCCAGATGT GGATCTCTTC CGGAAGCAGA AGCTCGTCGT 480

ATATTCCGAC AAATCACTTC TGCAGTCCTT TATTGCCATA AACATCGGGT TGCTCACAGA 540

GATTTAAAAT TGGAGAACAT TCTTTTAGAT CAAAATAATA ATGCAAAAAT TGCCGATTTT 600

GGTTTGTCCA ATTATTTCGC CGATAAGAAT CTTCTGACAA CATTCTGTGG AAGTCCATTG 660

TATGCATCTC CAGAAATTAT CAACGGAACA CCATATAAAG GTCCAGAAGT TGATTGTTGG 720

TCACTTGGAA TTCTTCTCTA TACTTTAGTT TATGGAAGTA TGCCTTTTGA TGGAAGAGAC 780

TTTAATCGAA TGGTCAGGCA AATCAAAAGA GGAGCCTATT TTGAGCCAGA GACACCGTCA 840

ACGGCATCAA TGTTAATCCG AAACATGCTT CGAGTAAACC CGGAGAGAAG AGCCACCATT 900

TTTGACATTG CATCCCATTG GTGGCTGAAT CTTGAAGAAA ATATGCCTGT GATTCAAGAA 960

CTTCCTGAAA ATCAAATTAT CGATCACACT CCTTTAACGG AAAGAGAAGA GACAATGATA 1020

GTACAAGATC TCGCTGATGA ACAAGACGTT TTCATGGAAT TCGGGCATCT TTCATCAGAG 1080

ACTCGTCGCA AGATTGAAGA CTTCAGAATA CGAAGAAAAG AGGCTGAGGA GTTTAATGAT 1140

AATTCACCGG TGAAACCTCC AAAAGCAAGG AAAACTGATG AATTAACTGG AAAAATTTCG 1200

AAAGAACAAC CGGAAGAGAT GAAGTCTGCT GAAAAATCTC TGAGAGGAGT AAAAGAGGAG 1260

AAAGAAAAAC CGAAAGTTGT TGATCCGAAT GATCCACTGG AAAGACTCAG ACAAATTGAA 1320

AATCGATTGG GACAAAATAA GAAAGACAAA GAGGCAGCAA AAACATCCGC CCGCGTTGAA 1380

ACAGTAAAAC TTAAAGAGGT GAAGAAAGAA AAGTCTCCAG AGCAACAACC AGAAGATCCG 1440

AAAACTGCAA GAGGAACATC AAAACCAGCT GATTCTCGTG CTCCATCATT CGTTCCAGTT 1500

AAGGATCGTC CAGAAACTTC TGAACCTGAA AGACCACGTA CTCGTCCACA TTTGACTGCA 1560

AGTGCCTACA GAATTGAAAC GGATTCTTTG AATATGTTGA TGAATCAAGT ACTCGAACAA 1620

ATGGAAAAAG GACCAGTCAA TTTGAATATT ATTGCAAGAA TCAAAGCCCA TCCACTATAT 1680

GACACAAGGC CAATGGTGAA AGAACTTTTG GAAAGTATTA TTGCTGCTCA GCCAGAGCCC 1740

GTGCAAAAGC AGACTAGCAA AGTGGTCGAG CAACAGACAT TCTCCCGCCA AAATACACTG 1800

ACGAGAAAGA AGAAAGAGGA TCCATTAGAA GAGGAGATCC CAGAAGTTCC ATCACCTTCA 1860

CGAAAGATGA AGGAGAGACC ATGGCATTCT GTAGAGGTTG GATTTGATCC TGACGAGGAA 1920

CCAGAGCATG ATCGCATGCA GGAATCAATT GCCAGCAATG CAACAGAAGT TACTGTACAA 1980

GATACTTCCT TTGAAGATGA TAGTTCTGAT GAAGAAGAGA GAAAGAAGAC GCCAGTTGCA 2040

TCAACACCAA AGACTCCAGT TCTAATTGTT GAAAAACAAG AAAGCTCAAC GAATGCGGAA 2100

GATGAAGAAA GTGATGAAGG AGATGATTAT AGTGATGCTG AAATGGAGGA ATTAGCTGAT 2160

GAAGTTGACA AGAAAGGACC GTCAGATTCT AAACTCGCTC CAGTTGTGGA GAATCTCGAA 2220

GCTAATCCGC CACCAGATCC ATCAAGTTCA CCTCAATTCC TTGATGCATT TGATAGAGGT 2280

CTCATTAAGA GACAAAGTAA AGGAAAATAT CAGGCAAAGG AAATTCTTCA AACATACCCT 2340

AACAATAAAT TGGATGCTCG TGGAATTGAT GTTGAGTTGA GACGGAAATT AAGAATGGAG 2400

AAGGTGAAAG CTGATCTTCT GAAACAGCCG AAAGACGGAG ATAAACCTAG AAATTCATAC 2460

GTTGGCAGTG TACCACCTCG TTCACCTCCT CCGATCGTTG TCAAGTCAGA TGGAGAAGAG 2520

CTTGATGATG AGGAAGAAGA AGAAGAGGAT GAGGAAGAGA TTGAGGAGAC TGATTCTGAA 2580

GAAGGATCTG ACTTTGAGAA TTTCAAACCA AAGCGTCCAA TTATTGCTGC AGTTCGACGA 2640

GATGATGGTG CTGTGGTGCC AGTGATTCAT CAAACTACTC GACCTGCTGT TGTTTCTCCA 2700

AACTCTCAAA ATCCACGTTA TCAAGTTGCT TCACCAAAAA CTTCGACGGT GATTCAGGCG 2760

ACTCCAGAAA AAGTACCGGT AGCAGGAACA TCTGCCAAAT ATCTTGTCAC GGTTGCTGAA 2820

TTGAAGCTGA AGCCTACGGA CAAGAAGGAG GAAGCTCAAT TGAAGGAGCA ATTGAAGGAC 2880

AGTGAGATCA ATAGTGAAAG AAAAGTGACA AAAGGAGCTG CACCGTCAAC AATTTCTCAA 2940

GATTCCGATG GTAAAGACAC GTTTGAGAGT GCTTCTGCAT ATATTCGACG CAAAAATCGA 3000

GAAAGACGTC AAAGAAATCG GACGATTGGA ACAGCAGAAG AAGCACTACG GGCTCTCGAG 3060

AGACCGTCTG TGGATCCATA CGATGATCGT GCATTCTCTC CTCTCTCGAC TGATCCATTT 3120

TATTCTCATC ACTCATCTGG TTCAGCTGCT CCATCAGCAC TTGGATATGT TCGACCTCGT 3180

TATCATGATG ATAGTTACCG TACTCATCGA GACAGTGATT ATCGTCCAAT GTCACCAACA 3240

AGTCGTTACA CAGCCGCTGT TACCAGAGAT GATCGTGGCA AATCAACATC GTACGACCCA 3300

CATGAAACCA CCAGACCATC GTACGATAGA GGCTACATAA CTTCATCCAA TGCAAGTCCA 3360

AGTTATACCC GGAAGTTTGA ACATGAGCAA CCAACATTGA ACTCATGGGC AAATGACCGT 3420

AAATTCGAAG TCTACAAAAC ACGGGCTGAA AGAGATGCTG AAAGGAATAC ATATCATCCA 3480

ACTGGAACTA CTGGTGCGAG CTCATATCGT CCATCTTCAT ATTATACATC AGCAAGTGAT 3540

AGACCCGTCA CTGGTCTAAG ACGTCCCGAA GAGAGTTATA CATCTTCAAC CAATTATGGG 3600

AGATATGATG GAAGATCAAC AACACCCAGC AACGACCAAT ACGCAATTTC AACGGCTTTG 3660

GCTGAAAATC AAGCTTCAAG TATGAATAAT CGTTTCCGTC CAACTGCTCG ACGCGTTGCA 3720

TCTGCAATGA CTGACGCAGA TCGTCGTAAT TATCACAGAT CAAGATCAAT GGATAGAAAT 3780

AAGGTTGATT ATGAATATGG AAGCAATTTG TTGAATAGAC TTACAACACC TGATTCTCAT 3840

GGAGACTACT CGTATGTAAA CTATCACGAC AGTTCAAATG GAAGATCTAA TATCACATTG 3900

GAAAAAGATG GACAGCCAAG GAGTATTCTG AAAAATAAAC AGAGTGCTGA CATCGAACCA 3960

CGTGTTGAAT CGTCTTATGA GCCAAGCAAT GGAGTTCGAT CGGTTGCATC TGTCGGACCA 4020

CATAGTCGAA ATATTGATAG CACATCATCT GCATTAGACA ATCCAAAAAA GAAAAGATCA 4080

TTGCTCTCAT TCAATCGGAG AAAGACAAGT GAAGTACGAA TGGGTGCCGA TGGAAAGCTG 4140

GTTACAAATG GATATGATAG TACACCGAGT AGCAGAGATT TCAAGAGACC AAGCTCCCCA 4200

ATCGATCGGA TAAAGTCTCT GTTCAGAAAG AATGAAAGTT CAGGAACTGG GCACTCGGAT 4260

TATTATAATT CTTCAAGAAA CTACACATCT TCAAATCCGG TTTCCACAAC TCGCGAGCCA 4320

TATGTTGCCC AATATAGAAA ATATCCAGGT TCAACCTCAC GTGATACGTC CAGCGCTCTC 4380

AATCGTTACT CATACACTCC TGGTCTAACA GATCAACGCC GTCATTGGTA TGATGATCCA 4440

AATATTTATT AA 4452

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         ++++k+lG+g++gkV+la +++ +++vavK+ikk+++ s+  l +i+rEi+i++ l+hpn

Q: 58    FEITKKLGSGTYGKVSLAYDHKFDREVAVKLIKKSAIeSKADLVRIRREIRIMSALNHPN  117

         6899******************************9996667789****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         ii+++ev+e+k+k++lv+ey sggeL+dy+++ g+l+e ear++f+q+ sav Y+h++++

Q: 118   IIQIYEVFENKDKIILVMEYSSGGELYDYVSRCGSLPEAEARRIFRQITSAVLYCHKHRV  177

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         +HrDlK+eN+lld+++n kiaDFGl+n+f +++ll+tfcGsp Ya+Pe+++g++Y+gp+v

Q: 178   AHRDLKLENILLDQNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEIINGTPYKGPEV  237

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+WslG++Ly+lv+g++Pfd++++++++++i++g +  p++  ++++ L+r++L v+pe+

Q: 238   DCWSLGILLYTLVYGSMPFDGRDFNRMVRQIKRGAYFEPET-PSTASMLIRNMLRVNPER  296

         ************************************88877.677899************

S: 240   Ratieeilkhewl  252

         Rati +i +h wl

Q: 297   RATIFDIASHWWL  309

         ************7

Domain Sequence
(FASTA)

FEITKKLGSG TYGKVSLAYD HKFDREVAVK LIKKSAIESK ADLVRIRREI RIMSALNHPN 60

IIQIYEVFEN KDKIILVMEY SSGGELYDYV SRCGSLPEAE ARRIFRQITS AVLYCHKHRV 120

AHRDLKLENI LLDQNNNAKI ADFGLSNYFA DKNLLTTFCG SPLYASPEII NGTPYKGPEV 180

DCWSLGILLY TLVYGSMPFD GRDFNRMVRQ IKRGAYFEPE TPSTASMLIR NMLRVNPERR 240

ATIFDIASHW WL 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

cel:CELE_B0496.3

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013