EKS-CAE-00046

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAE-00046

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	360.6	8.0E-108	238	519	282

Status

Unreviewed

Ensembl Protein

C07G1.3a

UniProt Accession

Q95QX1;

Protein Name

Protein Synonyms/Alias

Protein PCT-1, isoform b;

Gene Name

pct-1

Gene Synonyms/Alias

pct-1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
C07G1.3	C07G1.3a	C07G1.3a
C07G1.3	C07G1.3b	C07G1.3b
C07G1.3	C07G1.3c	C07G1.3c

Organism

Caenorhabditis elegans

Functional Description

Protein Length

577

Protein Sequence
(FASTA)

MKKLKRRLSA AFRPGSNNNV SITSSGGSYY DSDCEGRNNI VIGYGMMSAP LHGRTWTLSE 60

SMSHLSDKNG AILEECAVVD PTALLRVSRG GTAGRRYDTN VNYINGMHVP PPRTHSLYYP 120

RGYNSRRNSY YGSNASVVQE SMILGSDGES VEVSPCTSDQ TPTGVPPRYI VNVKMRQKTA 180

RKWSEEEIQK RLSLPADLRL PVAVVDKLNR TPTLDQPLTR KNRRASLSEI GFGKLETYEK 240

LDKLGEGTYA TVFRGRSILT NKFVALKEIR LEQEEGAPCT AIREVSLLRN LRHANVVTLH 300

DIIHTDRLLT LVFEYVDRDL KQYMDSCNNA MQMNNIRLFL YQLLRGLAYC HQRRVLHRDL 360

KPQNLLITAK GELKLADFGL ARAKSVPTKT YSNEVVTLWY RPPDVLLGST DYSTHIDMWG 420

VGCILFEMIA GRALFPGGTP TEQLGLIFRT LGSPRPDRHP TICEKPTFYP YANRHYNPDP 480

LCRQIPRIDA HGFELLMKFL QYEGKDRVSA AEAVKHPFLR TIAVKCCHLR DEQSVLEADG 540

IHIERELLAS DHHHSSRRHH RGTLVKDKYR MHSSHHT 577

Nucleotide Sequence
(FASTA)

ATGAAGAAGC TTAAACGGCG TTTGTCAGCA GCATTCCGTC CTGGAAGTAA CAATAATGTG 60

AGCATTACCA GTTCTGGAGG ATCTTATTAT GATTCGGATT GTGAAGGACG TAATAATATT 120

GTAATCGGTT ACGGTATGAT GTCAGCACCA CTTCATGGAA GAACTTGGAC ACTTTCCGAA 180

TCAATGAGCC ATTTATCAGA CAAAAATGGT GCAATTTTAG AAGAATGTGC AGTTGTTGAT 240

CCAACAGCAT TGCTTAGAGT TTCACGAGGA GGTACTGCTG GTAGACGATA TGATACAAAT 300

GTTAATTATA TCAACGGAAT GCATGTCCCA CCACCACGAA CACACAGTCT CTACTATCCA 360

CGTGGCTACA ATTCTCGTCG AAACTCATAT TACGGATCCA ATGCTTCGGT TGTCCAAGAA 420

TCGATGATTT TGGGATCAGA TGGAGAGAGT GTTGAAGTTT CTCCGTGTAC TTCTGATCAA 480

ACGCCAACAG GTGTTCCTCC TAGATACATT GTGAACGTGA AAATGCGACA GAAGACAGCT 540

AGAAAGTGGA GTGAGGAGGA AATCCAAAAG CGACTGTCAC TTCCTGCAGA TTTGCGTCTT 600

CCGGTTGCAG TTGTCGACAA GCTTAACAGA ACACCAACAT TGGATCAACC ACTGACACGA 660

AAGAATCGAA GAGCATCACT CAGTGAAATT GGCTTTGGAA AATTAGAGAC TTATGAGAAA 720

TTGGATAAAC TCGGTGAAGG GACGTATGCT ACCGTATTCC GAGGAAGATC CATTTTGACG 780

AACAAGTTTG TGGCACTAAA AGAAATACGT TTGGAACAAG AGGAGGGAGC ACCATGCACA 840

GCGATTCGCG AAGTTTCGTT ATTAAGGAAT CTTCGACACG CGAATGTTGT TACTTTACAT 900

GATATCATTC ATACGGATCG GTTATTAACA TTGGTATTCG AGTACGTGGA TCGTGATCTG 960

AAGCAATATA TGGATTCATG TAACAATGCA ATGCAAATGA ATAATATTCG ACTCTTCCTT 1020

TACCAACTTC TTCGAGGACT CGCCTACTGT CATCAACGAA GAGTTCTTCA TAGAGATTTG 1080

AAACCTCAAA ACTTGTTGAT TACTGCAAAA GGAGAGCTTA AACTTGCGGA TTTCGGACTG 1140

GCACGTGCCA AGTCCGTACC GACAAAGACG TATTCAAATG AGGTTGTCAC ATTATGGTAT 1200

AGGCCACCAG ATGTTCTTCT TGGTTCCACT GATTATTCGA CACATATTGA TATGTGGGGT 1260

GTTGGGTGTA TATTGTTTGA GATGATTGCT GGAAGAGCTC TTTTCCCAGG TGGTACACCA 1320

ACAGAGCAAC TTGGACTCAT TTTTAGAACA CTTGGATCTC CTCGACCGGA TCGACATCCG 1380

ACAATATGCG AAAAGCCAAC ATTCTATCCA TACGCTAACA GACATTACAA TCCAGATCCA 1440

CTTTGCCGTC AAATTCCACG GATTGATGCT CACGGATTCG AATTGCTCAT GAAATTCTTA 1500

CAGTACGAAG GAAAAGATCG AGTGTCGGCT GCTGAAGCTG TGAAGCATCC GTTCTTGAGG 1560

ACGATCGCTG TGAAGTGTTG CCACCTGCGA GATGAGCAAT CTGTCCTAGA AGCTGATGGT 1620

ATTCACATTG AAAGGGAACT TCTGGCATCA GATCATCATC ACAGCTCTCG TCGTCATCAT 1680

CGTGGAACTC TTGTAAAAGA TAAATATCGA ATGCATTCGA GTCATCACAC TTAG 1734

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yekl+k+geGty++v+++++  t+++vAlK+irle+e eg p+ta+rE+sll++l+h+n+

Q: 238   YEKLDKLGEGTYATVFRGRSILTNKFVALKEIRLEQE-EGAPCTAIREVSLLRNLRHANV  296

         99*********************************99.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ +++ l+Lvfe++++dLk++++++++  +++++++ +l+qll+glay+H+++

Q: 297   VTLHDIIH-TDRLLTLVFEYVDRDLKQYMDSCNN-AMQMNNIRLFLYQLLRGLAYCHQRR  354

         ********.999**********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg+++Yst

Q: 355   VLHRDLKPQNLLITAKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTDYST  414

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgcil e+++ ++lf+g + ++ql  if++lg+p+ + +p++ + p++  ++ +

Q: 415   HIDMWGVGCILFEMIAGRALFPGGTPTEQLGLIFRTLGSPRPDRHPTICEKPTFYpYANR  474

         *****************************************************9977888

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         ++++  l +++++++ ++++ll k+l+++ k+R+sa ea++h+++

Q: 475   HYNPDPLCRQIPRIDAHGFELLMKFLQYEGKDRVSAAEAVKHPFL  519

         88899*************************************996

Domain Sequence
(FASTA)

YEKLDKLGEG TYATVFRGRS ILTNKFVALK EIRLEQEEGA PCTAIREVSL LRNLRHANVV 60

TLHDIIHTDR LLTLVFEYVD RDLKQYMDSC NNAMQMNNIR LFLYQLLRGL AYCHQRRVLH 120

RDLKPQNLLI TAKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSTDYSTHID 180

MWGVGCILFE MIAGRALFPG GTPTEQLGLI FRTLGSPRPD RHPTICEKPT FYPYANRHYN 240

PDPLCRQIPR IDAHGFELLM KFLQYEGKDR VSAAEAVKHP FL 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0030424	; C:axon
GO:0030425	; C:dendrite
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

cel:CELE_C07G1.3

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013