EKS-CAE-00178

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-CAE-00178

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Ryk	434.3	2.4E-130	282	570	289

Status

Unreviewed

Ensembl Protein

C16B8.1.1

UniProt Accession

G5EGT9;

Protein Name

Protein Synonyms/Alias

Protein LIN-18; Tyrosine kinase receptor-related protein RYK;

Gene Name

lin-18

Gene Synonyms/Alias

lin-18; ryk;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
C16B8.1	C16B8.1.2	C16B8.1.2
C16B8.1	C16B8.1.1	C16B8.1.1

Organism

Caenorhabditis elegans

Functional Description

Protein Length

583

Protein Sequence
(FASTA)

MILRYLIFFA QLWALCLANV NMFISKEEMN RTFGVKAELN YIEMGNVSSY STKFHYRVMA 60

NIDYLSFTWN AVGIVHYEVY VESDDSSVLP IVRIPLKGTV PESLQDFTVE YRCAGHRSGQ 120

FAVSLYFTFK YGNKEPLKVK LRQEKICASR DGRRGLNGGY EGHEVDDTDS IDKAFFVIIC 180

IAAAFLLIVA ATLICYFKRS KKEDMIPTRL PTSFRNSLKS TKSAQPFLLS TPRDGPPTLS 240

AISSAPCSSS SASGNSIIPS KPRNIDVRRA LLQLYQDRDA FQSLPLDMEG TFGEVRYAIW 300

RQVDDVLNGD VDDEEDTFCN QEAVYTKTLK NNASPIQLDR FLSDALLFYN ITPHQNLSQV 360

ACVASFGRFD RPETVTDFPL VCYRHQGFGN LKKFLTICRH GDKTKGAQTL RTHQLVSLAT 420

QVSSAVAHIH KYRIVHNDIA ARNCLIAEVN GRLQVQLCDS ALSRDLFPAD YHCLGDNENR 480

PLKWMSPEAI ANELYSSAAD VWSLGVLLWE LMSLGGSPHA EIDPEEVYTM ILKGKRLQQP 540

NNCPDQLYEV MLCCWRVLSE DRPSSEQVVH GLRDFNIQLS QYI 583

Nucleotide Sequence
(FASTA)

ATGATTCTTC GCTACCTGAT TTTTTTCGCG CAGTTATGGG CACTCTGCCT GGCCAATGTG 60

AATATGTTCA TCAGCAAAGA GGAAATGAAT CGTACTTTTG GTGTCAAAGC TGAGCTGAAT 120

TACATTGAAA TGGGGAATGT TAGCTCGTAC TCTACAAAGT TTCACTACAG AGTTATGGCA 180

AACATCGACT ACCTCTCGTT CACATGGAAT GCTGTTGGAA TTGTACACTA TGAAGTTTAC 240

GTCGAATCTG ATGACTCTTC TGTGCTTCCT ATTGTTCGAA TTCCATTGAA AGGAACGGTG 300

CCAGAATCTT TGCAGGACTT CACCGTTGAA TACAGATGTG CCGGACACCG ATCCGGACAA 360

TTTGCTGTCA GTCTATATTT CACATTCAAA TATGGTAATA AGGAGCCGTT GAAAGTGAAA 420

TTGCGACAGG AGAAGATCTG CGCTTCAAGG GACGGACGTC GAGGTCTGAA CGGAGGCTAC 480

GAGGGTCATG AAGTCGACGA CACTGACTCA ATAGACAAGG CATTTTTTGT TATCATTTGC 540

ATTGCTGCGG CATTCCTACT TATTGTGGCA GCAACGTTGA TCTGTTATTT CAAGCGCTCT 600

AAAAAAGAAG ACATGATTCC GACTCGACTT CCAACGTCTT TTCGGAATTC TTTGAAATCT 660

ACAAAAAGCG CGCAGCCTTT TCTTCTGAGC ACACCGCGAG ATGGACCTCC GACTCTTTCC 720

GCTATTTCAA GCGCTCCTTG TTCTTCGTCG TCTGCGTCGG GAAATTCGAT AATCCCGAGC 780

AAGCCAAGAA ACATTGACGT GAGACGTGCA TTGTTACAAC TCTATCAAGA TCGAGATGCT 840

TTTCAATCTC TACCTCTAGA TATGGAGGGA ACATTTGGAG AAGTGAGATA TGCAATTTGG 900

CGTCAAGTAG ATGACGTACT GAACGGAGAT GTTGACGACG AAGAAGACAC ATTCTGTAAC 960

CAGGAAGCTG TTTACACCAA AACGTTGAAA AATAATGCCT CACCAATTCA GCTGGATCGG 1020

TTTTTGTCCG ACGCCCTTCT ATTTTACAAC ATCACACCTC ACCAAAACTT GTCTCAAGTG 1080

GCATGTGTGG CTTCCTTCGG AAGATTCGAC CGCCCGGAAA CTGTCACAGA TTTTCCACTT 1140

GTTTGTTACA GACACCAAGG CTTTGGAAAC CTGAAGAAGT TCCTCACCAT CTGCCGACAT 1200

GGTGATAAAA CTAAAGGAGC TCAAACTCTC CGAACTCATC AACTCGTCTC TCTGGCCACA 1260

CAAGTATCTT CTGCAGTAGC TCATATACAC AAATATAGAA TAGTGCATAA CGACATTGCC 1320

GCTAGAAACT GCTTGATCGC AGAAGTGAAT GGGCGACTCC AAGTGCAATT ATGCGACTCG 1380

GCGCTGTCCC GCGATCTGTT CCCAGCTGAT TATCACTGCT TGGGTGACAA TGAGAACAGA 1440

CCATTGAAAT GGATGTCTCC AGAAGCTATT GCAAATGAGC TGTACTCATC GGCCGCTGAT 1500

GTTTGGTCAC TGGGAGTTCT ACTGTGGGAG CTCATGTCGC TAGGAGGATC TCCACACGCT 1560

GAAATAGACC CTGAGGAAGT GTACACAATG ATTCTCAAAG GAAAGCGTCT GCAACAGCCG 1620

AACAATTGTC CGGATCAATT ATACGAAGTC ATGCTGTGCT GTTGGAGGGT ACTCAGCGAA 1680

GATCGTCCTA GCAGTGAGCA GGTAGTTCAT GGACTTCGAG ACTTTAACAT TCAACTCAGT 1740

CAATACATCT AA 1752

Domain Profile

S: 2     rlkellqeGtfGr...........iyrGkledekdt.nkekavlvktvkdqaseiqvall  49

         ++ +l++eGtfG+           +++G+++de+dt ++++av++kt+k++as+iq++++

Q: 282   QSLPLDMEGTFGEvryaiwrqvddVLNGDVDDEEDTfCNQEAVYTKTLKNNASPIQLDRF  341

         6789********************************************************

S: 50    lqealllygvshrnilsvllvsieeaek..........Plvvypalnkgnlkkflrickl  99

         l++all+y+++++++ls++ ++++++++          Plv+y+++++gnlkkfl+ic++

Q: 342   LSDALLFYNITPHQNLSQV-ACVASFGRfdrpetvtdfPLVCYRHQGFGNLKKFLTICRH  400

         *******************.****************************************

S: 100   kdkek.aqalstkqlvelaiqiasalaylhkrevvhkdiaarncvidd...elqvkltds  155

          dk+k aq+l+t+qlv+la+q++sa+a++hk+++vh+diaarnc+i++   +lqv+l+ds

Q: 401   GDKTKgAQTLRTHQLVSLATQVSSAVAHIHKYRIVHNDIAARNCLIAEvngRLQVQLCDS  460

         *****9******************************************999*********

S: 156   alsrdlfPadydclGdnenrPlkWlslealqkeeyssasdvWalGvllWelvtlgksPya  215

         alsrdlfPady+clGdnenrPlkW+s+ea+++e yssa+dvW+lGvllWel++lg+sP+a

Q: 461   ALSRDLFPADYHCLGDNENRPLKWMSPEAIANELYSSAADVWSLGVLLWELMSLGGSPHA  520

         ************************************************************

S: 216   eidpfeleaylkdGyrlaqPvncPdelftvmaccWallpeerPsfeqlvs  265

         eidp+e+++++ +G+rl+qP+ncPd+l++vm+ccW++l+e+rPs+eq+v+

Q: 521   EIDPEEVYTMILKGKRLQQPNNCPDQLYEVMLCCWRVLSEDRPSSEQVVH  570

         ************************************************96

Domain Sequence
(FASTA)

QSLPLDMEGT FGEVRYAIWR QVDDVLNGDV DDEEDTFCNQ EAVYTKTLKN NASPIQLDRF 60

LSDALLFYNI TPHQNLSQVA CVASFGRFDR PETVTDFPLV CYRHQGFGNL KKFLTICRHG 120

DKTKGAQTLR THQLVSLATQ VSSAVAHIHK YRIVHNDIAA RNCLIAEVNG RLQVQLCDSA 180

LSRDLFPADY HCLGDNENRP LKWMSPEAIA NELYSSAADV WSLGVLLWEL MSLGGSPHAE 240

IDPEEVYTMI LKGKRLQQPN NCPDQLYEVM LCCWRVLSED RPSSEQVVH 289

Keyword

Complete proteome; Kinase; Receptor; Reference proteome; Signal; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>