EKS-ANC-00245

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00245

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	287.3	8.6E-86	9	265	257

Status

Unreviewed

Ensembl Protein

ENSACAP00000000152

UniProt Accession

H9G3B5;

Protein Name

Protein Synonyms/Alias

Gene Name

CHEK1

Gene Synonyms/Alias

CHEK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000000155	ENSACAP00000000152	ENSACAT00000000155

Organism

Anolis carolinensis

Functional Description

Protein Length

475

Protein Sequence
(FASTA)

MAVPFVEDWD LVQTLGEGAY GEVQLAVNRR TEEAVAVKIV DMKRAIECPE QIKKEICINK 60

MLSHENIVKF YGHRREGTIQ YLFLEYCSGG ELFDRIEPDI GMPEAEAQRF FHQLIGGVVY 120

LHSLGVTHRD IKPENLLLDE RDNLKISDFG LATVFKYNGR ERLLNKICGT LPYVAPEVLK 180

RKEFHAEPVD VWSCGIVLTA MLAGELPWDQ PTETCQEYCD WKEQKSYLAP WKKIDSLPLA 240

LLIKILTENP ASRLTIADIK KDKWYTKLLQ KGIKRSRIST EPSDSPGVFS KHIRSDTDFS 300

PVKDTHSEER RTYSNSQPEP GTGLSFWDNS PANIDKLVQG ISFSQPACPE HMLLNSQLLG 360

TPGSSQNPWQ RLVKRMTRFF LKLDAEQSYE ILKEVCDKMG YIWKKGCTNE VTISTTDRRN 420

NKLIFKANLV EMDEKILVDF RLSKGDGLEF KRHFLKIKGK LVDVVSAQKL WLPAT 475

Nucleotide Sequence
(FASTA)

ATGGCAGTGC CTTTTGTAGA AGATTGGGAC TTGGTGCAAA CCCTTGGAGA AGGTGCTTAT 60

GGAGAAGTTC AACTGGCAGT GAACAGACGC ACTGAAGAAG CAGTTGCAGT CAAAATTGTT 120

GACATGAAGC GTGCCATTGA ATGTCCAGAA CAGATTAAGA AGGAGATCTG CATCAACAAA 180

ATGTTGAGTC ATGAGAACAT AGTGAAGTTC TATGGCCATC GGCGAGAAGG CACTATTCAG 240

TATCTTTTCC TTGAATACTG CAGCGGAGGG GAGCTGTTTG ACCGAATAGA GCCTGATATA 300

GGGATGCCTG AAGCAGAAGC ACAGAGGTTT TTTCACCAGC TTATAGGTGG TGTGGTCTAC 360

CTACACAGCT TAGGAGTAAC ACATCGGGAT ATTAAGCCTG AGAATCTGTT GCTGGATGAA 420

AGAGATAATC TCAAAATATC CGACTTTGGC CTAGCAACTG TGTTTAAATA CAATGGACGT 480

GAGCGTTTGT TGAACAAGAT CTGTGGCACG TTGCCATATG TTGCACCCGA GGTCCTTAAA 540

AGAAAAGAAT TCCATGCAGA GCCAGTTGAT GTTTGGTCTT GTGGAATAGT ACTCACTGCT 600

ATGTTGGCAG GAGAATTACC ATGGGATCAA CCTACTGAAA CTTGTCAAGA ATATTGTGAC 660

TGGAAAGAAC AGAAATCATA TCTTGCACCA TGGAAGAAGA TTGATTCATT ACCACTGGCT 720

TTGCTTATCA AAATATTAAC TGAGAACCCA GCATCCAGAC TGACCATAGC AGACATTAAA 780

AAAGACAAGT GGTACACCAA ACTTTTACAG AAAGGCATAA AACGGTCTCG GATCTCCACA 840

GAACCCTCTG ATTCTCCAGG AGTTTTTTCT AAGCACATTC GATCAGATAC TGACTTCTCT 900

CCAGTGAAAG ACACACACAG TGAGGAAAGA AGGACCTATT CCAATTCTCA GCCAGAACCT 960

GGCACTGGCC TATCCTTTTG GGACAACAGT CCTGCCAATA TTGACAAGCT AGTGCAAGGC 1020

ATCAGCTTCT CCCAGCCAGC CTGCCCGGAA CACATGCTGC TGAACAGCCA ACTATTGGGC 1080

ACTCCAGGCT CCTCTCAGAA TCCATGGCAG CGCTTGGTGA AGAGAATGAC CCGGTTCTTT 1140

TTGAAGTTGG ATGCGGAGCA GTCGTATGAG ATCCTGAAGG AGGTTTGCGA TAAGATGGGC 1200

TACATCTGGA AGAAGGGCTG CACAAACGAG GTTACCATAT CAACAACCGA TAGAAGAAAC 1260

AACAAACTGA TTTTCAAGGC AAACTTAGTA GAAATGGATG AGAAAATTCT TGTGGACTTC 1320

CGTCTGTCTA AGGGCGATGG TTTGGAGTTC AAGAGGCATT TCCTGAAGAT CAAGGGGAAA 1380

CTGGTCGACG TTGTCAGTGC GCAGAAGTTG TGGCTCCCAG CCACATGA 1428

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         ++l++tlGeg++g+V+la++++t+e+vavKi++ k++  e  e+ik+Ei i k+l+h+ni

Q: 9     WDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAI-ECPEQIKKEICINKMLSHENI  67

         7899******************************7765.5579*****************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         +k++   ++ +  yl+ley+sggeLfd+ie +  ++e ea+++f+ql+ +v Ylhs g++

Q: 68    VKFYGHRREGTIQYLFLEYCSGGELFDRIEPDIGMPEAEAQRFFHQLIGGVVYLHSLGVT  127

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkeg...klletfcGsppYaaPellkgkkYegp  177

         HrD+KpeNllld+++n+ki+DFGla++fk++   +ll++ cG++pY+aPe+lk+k+++++

Q: 128   HRDIKPENLLLDERDNLKISDFGLATVFKYNgreRLLNKICGTLPYVAPEVLKRKEFHAE  187

         **************************999988889*************************

S: 178   kvDvWslGvvLyalvtgklPfdee..nlkellekilkgkleipkk.lskelesLlrklLv  234

         +vDvWs+G+vL a+++g+lP+d++  +++e+ ++ +++++  p k +++    Ll k+L+

Q: 188   PVDVWSCGIVLTAMLAGELPWDQPteTCQEYCDWKEQKSYLAPWKkIDSLPLALLIKILT  247

         ***********************977899***********999888**************

S: 235   vdpekRatieeilkhewl  252

         ++p++R+ti +i+k++w+

Q: 248   ENPASRLTIADIKKDKWY  265

         *****************5

Domain Sequence
(FASTA)

WDLVQTLGEG AYGEVQLAVN RRTEEAVAVK IVDMKRAIEC PEQIKKEICI NKMLSHENIV 60

KFYGHRREGT IQYLFLEYCS GGELFDRIEP DIGMPEAEAQ RFFHQLIGGV VYLHSLGVTH 120

RDIKPENLLL DERDNLKISD FGLATVFKYN GRERLLNKIC GTLPYVAPEV LKRKEFHAEP 180

VDVWSCGIVL TAMLAGELPW DQPTETCQEY CDWKEQKSYL APWKKIDSLP LALLIKILTE 240

NPASRLTIAD IKKDKWY 257

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

acs:100564808

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013