EKS-ANC-00308

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00308

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	341.3	3.5E-102	20	272	253

Status

Unreviewed

Ensembl Protein

ENSACAP00000001074

UniProt Accession

G1K945;

Protein Name

Protein Synonyms/Alias

Gene Name

STK25

Gene Synonyms/Alias

STK25;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000000971	ENSACAP00000001074	ENSACAT00000001103

Organism

Anolis carolinensis

Functional Description

Protein Length

428

Protein Sequence
(FASTA)

SNHTFFLLTQ HSRVDPEELF TKLERIGKGS FGEVYKGIDN RTKEVVAIKI IDLEEAEDEI 60

EDIQQEITVL SQCDSPYITR YYGSYLKGTK LWIIMEYLGG GSALDLLKPG PLEETYIATI 120

LREILKGLDY LHCERKIHRD IKETAANVLL SEQGDVKLAD FGVAGQLTDT QIKRNTFVGT 180

PFWMAPEVIK QSAYDFKADI WSLGITAIEL AKGEPPNSDL HPMRVLFLIP KNNPPTLEGH 240

HSKPFKEFVE ACLNKDPRFR PTAKELLKHK FITRYTKKTS FLMELIDRYK RWKSEGHGED 300

SSSDDSDIDG DADERDQGPM WTFPPTIRPN SLNKLHKGLS HHGSQKPAEP IKRQPRSQSL 360

STLVRPVFGE LKDKHKQTGG NVGAMEELEN AFGLAEESCP GISDKLIAHM VERVQRFSHS 420

RNHLTSAR 428

Nucleotide Sequence
(FASTA)

TCCAATCATA CTTTTTTTCT GCTAACCCAG CACTCTAGGG TTGATCCAGA GGAACTCTTC 60

ACCAAGCTGG AAAGGATCGG TAAAGGGTCT TTTGGAGAGG TGTACAAAGG AATTGATAAC 120

CGCACTAAGG AAGTGGTAGC GATCAAGATC ATTGACCTTG AGGAGGCTGA AGATGAGATT 180

GAGGATATCC AGCAAGAGAT TACGGTGCTT AGCCAGTGCG ACAGCCCCTA TATCACCCGC 240

TACTATGGTT CCTATTTGAA GGGCACCAAA CTCTGGATAA TCATGGAGTA CTTGGGAGGA 300

GGCTCAGCAC TGGATCTACT CAAGCCTGGT CCCTTAGAAG AGACCTATAT TGCCACCATT 360

CTGCGGGAAA TTCTCAAGGG TTTGGACTAC CTTCATTGTG AGAGGAAAAT CCACAGAGAC 420

ATCAAAGAAA CAGCAGCCAA CGTGCTACTT TCAGAACAAG GAGATGTGAA GCTAGCTGAT 480

TTTGGTGTGG CTGGCCAACT GACAGACACT CAGATCAAGA GAAACACTTT TGTTGGGACC 540

CCTTTTTGGA TGGCACCCGA AGTCATCAAG CAATCAGCCT ATGACTTCAA GGCAGATATT 600

TGGTCCCTTG GCATTACTGC TATTGAACTG GCAAAGGGAG AGCCTCCGAA TTCCGACTTG 660

CATCCTATGA GAGTTCTTTT CCTGATTCCC AAAAACAACC CTCCAACTTT AGAGGGACAC 720

CACAGTAAGC CCTTTAAGGA ATTTGTGGAG GCCTGCCTTA ACAAGGACCC TCGATTTAGG 780

CCCACTGCAA AGGAACTGCT AAAGCACAAA TTTATTACAC GTTACACCAA AAAAACATCA 840

TTTCTCATGG AGCTCATTGA TCGGTACAAG CGCTGGAAGT CAGAGGGGCA TGGTGAGGAT 900

TCAAGCTCCG ATGACTCCGA CATTGATGGA GATGCAGATG AACGGGATCA AGGACCCATG 960

TGGACTTTCC CACCAACCAT TCGCCCCAAT TCGCTGAACA AGTTGCACAA GGGACTGTCT 1020

CATCATGGGT CCCAAAAGCC TGCTGAACCC ATCAAACGGC AGCCACGGTC TCAGTCTCTC 1080

TCTACTCTGG TTCGCCCTGT CTTTGGAGAG CTCAAAGACA AGCATAAGCA GACTGGAGGG 1140

AATGTAGGAG CCATGGAGGA ACTGGAGAAT GCCTTTGGCT TAGCTGAAGA ATCTTGTCCA 1200

GGAATCTCTG ACAAATTAAT TGCACATATG GTGGAGCGAG TGCAAAGGTT CTCACACAGC 1260

AGGAACCACC TGACTTCGGC ACGCTGA 1287

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         ++ le+igkG++g+vy++ +++t+e+vaik+i+le+  +++e++q+ei+vl+++++p+i+

Q: 20    FTKLERIGKGSFGEVYKGIDNRTKEVVAIKIIDLEEAeDEIEDIQQEITVLSQCDSPYIT  79

         7889*******************************99899********************

S: 60    eylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkv  119

         +y++s+lk ++lw++meyl gGs+ dl+k     +l+E+ ia+ilre+lk+L+ylH +++

Q: 80    RYYGSYLKGTKLWIIMEYLGGGSALDLLK---PGPLEETYIATILREILKGLDYLHCERK  136

         *****************************...****************************

S: 120   iHrdik..akniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgY  177

         iHrdik  a+n+Ll+e+g+VkL+dfgva ql++t+ kr+t+vgtp+wmAPEvi+  ++ Y

Q: 137   IHRDIKetAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIK--QSAY  194

         *****97779********************************************..9***

S: 178   dekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekc  237

         d kaDiwslGItaiela+gepP +dl+p+++l++i+kn+pp+l+ +   sk fkefve+c

Q: 195   DFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLEGH--HSKPFKEFVEAC  252

         *******************************************666..9***********

S: 238   lqknpekRpsasellkhkFl  257

         l+k+p++Rp+a+ellkhkF+

Q: 253   LNKDPRFRPTAKELLKHKFI  272

         *******************7

Domain Sequence
(FASTA)

FTKLERIGKG SFGEVYKGID NRTKEVVAIK IIDLEEAEDE IEDIQQEITV LSQCDSPYIT 60

RYYGSYLKGT KLWIIMEYLG GGSALDLLKP GPLEETYIAT ILREILKGLD YLHCERKIHR 120

DIKETAANVL LSEQGDVKLA DFGVAGQLTD TQIKRNTFVG TPFWMAPEVI KQSAYDFKAD 180

IWSLGITAIE LAKGEPPNSD LHPMRVLFLI PKNNPPTLEG HHSKPFKEFV EACLNKDPRF 240

RPTAKELLKH KFI 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0007163	; P:establishment or maintenance of cell polarity
GO:0051645	; P:Golgi localization

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013