EKS-ANC-00107

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00107

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	341.6	2.9E-102	1	265	265

Status

Unreviewed

Ensembl Protein

ENSACAP00000001613

UniProt Accession

H9G5F1;

Protein Name

Protein Synonyms/Alias

Gene Name

GAK

Gene Synonyms/Alias

GAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000001376	ENSACAP00000001613	ENSACAT00000001652

Organism

Anolis carolinensis

Functional Description

Protein Length

1269

Protein Sequence
(FASTA)

GGFAFVYEAQ DLGSGKDYAL KRLLSNEEEK NKAIIQEVCF MKKLSGHPNI VQFCSAASIG 60

KEESDTGQGE FLLLTELCRG QLVEFLKKAE SKGSLSCDTV LKIFYQTCRA VQHMHKQKPP 120

IIHRDLKIEN MLMSNQGTIK LCDFGSATNV AHYPDYNWTA QKRATVEEEI TRNTTPMYRT 180

PEIIDLYSNF PINEKQDIWA LGCILYLLCF RQHPFEDGAK LRIVNGKYSI PQNDTRYTVF 240

HDIIRSALKV NPEERLSITE LVNQLQEIAA ARNVNPKSPI TELLEQNGGY GNNAQPKTPS 300

TQVPQNSKPV GQLNNMYNAG LTVAECDQTY AGFFDILRGG TERFFTNIKD TSSKVIQSVA 360

NYAKGDLDIS YITSRIAVMS FPAEGVESAI KNNIEDVRLF LDSKHPGRYA VYNLSPRTYR 420

PSRFHNRVSE CGWPARRAPN LQNLYSICKN MHLWLKQDPK NVCIVHCLDG RAASAVVICS 480

FLCFCRLFTT AEAAVYMFSM KRCPPGIWPS HKRYIEYMCD MMADEPIIPH SKPILIKSIV 540

MTPVPLFSKQ RNGCRPFCEV YVGDERVATT SQEYDKMKDF KIEDGKAVIP LGITVQGDVL 600

IVIYHARSTL GGRLQAKMAS MKMFQIQFHT GFVPRNATTV KFATYDLDAC DIQEKYPDLF 660

QVNLEVEVEP RDRPSTERAP WDNLNIKGLN PKILFSSREE QQEILTKFGK PELPRQPGST 720

AQYEAEASKS ELSSEDTPVE PDSPPSSNTE ANFFQTLDWQ EGKHSDVGPE GYVSKECPGL 780

IDEREESEPS DEEFAAFPSE ARAAEEKERN TPGKENSEQL FEADFEMSSA QSKDTLVEDS 840

VDLLGLDSET PPELLQPPSE MKSSSSNADL LNDLFVSGLP ENSEDSTTDL LGGDPLPSRN 900

LHSPIRGLSP GIADPFDPFT VNPDNPTLTG PDLFGDFLSP NASTGSNMFP STHSAPPPSS 960

STEFLNLGGL APDPPKMTSS ASQPDLLGGW DSWADSPPVS TPTPATSKKT TLEGGPTNVP 1020

SGLSFNQAKS QNFDPFADLA NLKAGLPGAS SGGFSAGSFA PKSTPSQKTG HPWQANKPQA 1080

TSSSWQSHSQ PKPPEQAKPS VQPKPNYTVN FSVIGGREER GIRAPGFGQK PKVSENDFED 1140

LLSNQGFAAK SDRKGPKTIA EMRKQEMSRD MDPLKLKILD WIDGKERNIR ALLSTLHTVL 1200

WEGETKWKPC GMADLVTPDQ VKKYYRKAVL VVHPDKATGQ PYEQYAKMIF MELNDAWSEF 1260

ESQGSKSLF 1269

Nucleotide Sequence
(FASTA)

GGTGGTTTTG CTTTTGTTTA TGAAGCTCAG GATCTTGGAA GTGGCAAAGA TTATGCTTTA 60

AAGAGACTGC TATCTAATGA AGAGGAAAAG AACAAAGCCA TCATTCAAGA AGTTTGTTTT 120

ATGAAAAAGC TATCCGGCCA TCCAAATATT GTCCAGTTCT GCTCTGCTGC ATCCATAGGA 180

AAAGAAGAAT CTGATACTGG GCAAGGGGAA TTTCTTCTGC TCACTGAGCT TTGTAGAGGG 240

CAACTGGTGG AATTTTTAAA GAAAGCTGAA TCCAAAGGGT CCCTCTCCTG TGATACAGTT 300

CTCAAGATAT TTTACCAGAC GTGCAGAGCA GTACAACACA TGCACAAACA GAAGCCTCCA 360

ATCATTCATA GAGATCTAAA GATTGAAAAT ATGCTGATGA GTAACCAAGG GACCATTAAA 420

TTGTGTGATT TTGGCAGCGC AACAAATGTA GCACATTATC CAGACTACAA CTGGACAGCA 480

CAGAAAAGAG CAACCGTCGA AGAGGAGATC ACAAGGAACA CAACACCCAT GTATCGGACT 540

CCTGAAATAA TAGATTTATA TTCAAATTTT CCAATCAACG AAAAACAGGA TATATGGGCT 600

TTGGGTTGCA TCCTCTACTT GCTCTGCTTT AGGCAGCATC CGTTTGAAGA TGGAGCTAAG 660

CTTCGAATAG TCAATGGAAA ATATTCCATC CCACAAAACG ACACAAGATA TACAGTGTTT 720

CATGATATCA TTCGGTCTGC TTTAAAAGTG AATCCAGAAG AGAGATTGTC TATTACTGAG 780

CTTGTAAATC AGCTCCAAGA GATTGCAGCT GCGAGGAATG TAAACCCAAA GTCTCCCATC 840

ACAGAGCTTC TTGAGCAAAA TGGAGGCTAT GGAAATAATG CTCAGCCTAA GACACCTTCG 900

ACTCAGGTTC CACAGAACTC CAAGCCTGTA GGGCAACTCA ACAACATGTA TAATGCAGGC 960

CTTACTGTAG CAGAATGTGA CCAGACCTAT GCAGGGTTCT TCGATATTCT TAGGGGTGGG 1020

ACAGAGAGGT TTTTCACCAA TATCAAGGAC ACATCTTCAA AAGTGATTCA GTCTGTGGCC 1080

AATTATGCAA AAGGAGATCT GGATATATCC TATATCACCT CCAGAATTGC TGTAATGTCC 1140

TTTCCAGCAG AAGGTGTTGA GTCTGCCATA AAGAATAACA TTGAAGATGT GCGGTTATTC 1200

TTGGACTCTA AACATCCCGG CCGCTATGCT GTCTACAATC TGTCTCCAAG AACATATAGG 1260

CCTTCAAGAT TTCACAATCG GGTGTCCGAA TGTGGCTGGC CAGCAAGACG CGCACCCAAT 1320

CTTCAAAATC TGTATAGCAT TTGCAAGAAC ATGCATTTAT GGTTAAAACA AGACCCAAAG 1380

AATGTTTGCA TTGTGCACTG CCTTGATGGA AGAGCAGCAT CAGCTGTTGT CATTTGTTCC 1440

TTTTTATGTT TTTGCCGTCT GTTCACTACT GCTGAAGCTG CTGTCTACAT GTTTAGCATG 1500

AAGCGCTGCC CACCGGGTAT CTGGCCATCA CATAAGAGAT ATATAGAGTA CATGTGTGAC 1560

ATGATGGCGG ACGAACCTAT TATTCCTCAC AGCAAGCCAA TCCTCATAAA GTCTATTGTC 1620

ATGACACCAG TCCCTCTTTT CAGCAAGCAG CGCAATGGCT GTCGGCCCTT CTGTGAAGTT 1680

TATGTTGGGG ATGAAAGAGT AGCCACTACC TCACAAGAAT ACGATAAAAT GAAGGATTTT 1740

AAAATAGAAG ATGGAAAAGC AGTAATTCCA TTAGGCATAA CAGTCCAAGG AGATGTTCTC 1800

ATTGTGATCT ATCATGCCAG GTCCACCTTG GGTGGCAGAC TCCAGGCCAA GATGGCATCA 1860

ATGAAGATGT TCCAGATCCA GTTTCATACA GGATTCGTCC CCCGAAACGC CACAACTGTG 1920

AAATTTGCAA CGTATGATCT GGATGCCTGC GACATTCAGG AGAAGTATCC TGATTTGTTC 1980

CAAGTGAATC TGGAAGTTGA AGTGGAGCCA CGGGATAGAC CCAGCACTGA ACGAGCCCCC 2040

TGGGATAACT TGAACATCAA GGGTTTAAAT CCCAAGATCC TTTTCTCCAG CCGTGAGGAA 2100

CAGCAAGAGA TATTAACAAA ATTTGGTAAA CCTGAACTAC CCAGACAGCC CGGGTCAACT 2160

GCACAATATG AAGCAGAAGC ATCTAAGTCA GAACTGTCTT CTGAAGATAC ACCTGTGGAA 2220

CCAGACTCTC CACCCAGCAG TAACACAGAG GCAAATTTCT TCCAAACACT CGATTGGCAA 2280

GAAGGAAAAC ATTCAGATGT TGGACCAGAG GGCTACGTTT CTAAAGAGTG TCCAGGGCTA 2340

ATTGATGAAA GGGAGGAGAG CGAACCTTCT GATGAAGAAT TTGCTGCATT TCCCAGTGAA 2400

GCTAGAGCAG CTGAAGAAAA AGAGAGGAAC ACACCAGGGA AAGAAAACAG TGAGCAGCTT 2460

TTTGAAGCTG ACTTTGAAAT GTCTTCTGCA CAGTCCAAAG ATACTCTTGT GGAAGACAGT 2520

GTTGACTTGC TTGGACTGGA TTCAGAAACA CCACCAGAAC TCCTCCAACC TCCTTCAGAG 2580

ATGAAGAGTT CCTCTAGCAA TGCGGACTTG CTGAATGACC TATTTGTTAG TGGTCTGCCA 2640

GAGAATTCAG AAGACTCTAC TACAGACCTT CTGGGTGGAG ACCCTCTGCC ATCCAGAAAT 2700

CTCCATTCTC CTATTAGAGG GCTAAGCCCT GGTATAGCTG ACCCATTTGA CCCATTCACA 2760

GTCAATCCAG ACAATCCAAC TCTTACGGGT CCTGATCTCT TTGGCGACTT TCTCAGTCCA 2820

AATGCATCAA CTGGATCAAA TATGTTTCCT TCCACACACA GTGCACCACC TCCTTCTTCT 2880

AGCACAGAGT TCCTTAATTT AGGAGGTTTG GCACCAGATC CACCTAAAAT GACTTCCTCT 2940

GCAAGTCAGC CAGATCTTTT AGGCGGCTGG GATTCTTGGG CAGATTCCCC TCCAGTTAGC 3000

ACTCCAACAC CGGCAACGTC TAAGAAGACA ACCCTGGAAG GAGGCCCTAC AAATGTTCCC 3060

TCAGGCCTCT CCTTCAATCA AGCAAAATCG CAGAACTTTG ATCCTTTCGC TGACCTTGCT 3120

AACCTGAAAG CTGGCCTTCC AGGTGCTTCA AGTGGGGGTT TCTCAGCTGG TAGTTTTGCC 3180

CCGAAATCCA CTCCTTCACA AAAGACTGGG CATCCGTGGC AGGCCAACAA ACCACAAGCA 3240

ACTAGCTCAT CATGGCAATC TCACTCACAA CCAAAACCAC CAGAACAAGC CAAGCCGAGT 3300

GTACAGCCGA AACCCAACTA CACAGTGAAT TTCAGCGTTA TTGGCGGACG TGAAGAGAGA 3360

GGCATCAGAG CCCCAGGCTT TGGACAAAAA CCCAAAGTGT CAGAAAACGA TTTTGAAGAT 3420

CTGTTGTCAA ATCAAGGGTT TGCCGCAAAA TCTGACAGAA AAGGACCAAA GACCATTGCA 3480

GAGATGAGAA AACAAGAAAT GTCTAGAGAT ATGGACCCTC TAAAATTAAA GATTTTAGAT 3540

TGGATTGATG GAAAAGAGAG GAATATAAGA GCTTTATTAT CTACTCTTCA CACTGTGCTT 3600

TGGGAAGGTG AAACCAAATG GAAACCATGT GGCATGGCAG ACCTGGTTAC CCCAGATCAA 3660

GTGAAGAAGT ACTATAGGAA GGCAGTGCTT GTGGTTCATC CAGATAAGGC CACAGGGCAG 3720

CCTTATGAAC AGTATGCCAA AATGATCTTC ATGGAGCTGA ATGATGCGTG GTCAGAATTT 3780

GAAAGTCAAG GCTCAAAATC ACTTTTCTAA 3810

Domain Profile

S: 10    GGfalvylaedastgekyalKrilvneeedleeikrEieimkklsghknivklv..dssv  67

         GGfa+vy a+d+ +g+ yalKr+l+neee++++i++E+++mkklsgh+niv+++  +s

Q: 1     GGFAFVYEAQDLGSGKDYALKRLLSNEEEKNKAIIQEVCFMKKLSGHPNIVQFCsaASIG  60

         9*****************************************************777888

S: 68    keekdngskevlllleyckkgslvdllnkrlekgelseaeilkilldvtravaalHalsv  127

         kee+d+g+ e+lll+e+c+ g+lv++l+k ++kg+ls++++lki+++++rav+++H++++

Q: 61    KEESDTGQGEFLLLTELCR-GQLVEFLKKAESKGSLSCDTVLKIFYQTCRAVQHMHKQKP  119

         999***************9.8***************************************

S: 128   pliHRDlkveNillsdegelvlcDlGSattaileve...skqelsalqeeieknttlsyr  184

         p+iHRDlk+eN+l+s++g+++lcD+GSat+  + ++   ++q++++++eei++ntt++yr

Q: 120   PIIHRDLKIENMLMSNQGTIKLCDFGSATNVAHYPDynwTAQKRATVEEEITRNTTPMYR  179

         ***********************************999999*******************

S: 185   sPElidlysnlvideksDiWaLGcllYklcffesPfeesvklailngkysiPensrysek  244

         +PE+idlysn++i+ek+DiWaLGc+lY lcf+++Pfe+++kl+i+ngkysiP+n++ ++

Q: 180   TPEIIDLYSNFPINEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPQNDTRYTV  239

         ************************************************************

S: 245   lkslikkmlevdpeeRptiaqvlell  270

         ++++i++ l+v+peeR++i++++++l

Q: 240   FHDIIRSALKVNPEERLSITELVNQL  265

         **********************9986

Domain Sequence
(FASTA)

GGFAFVYEAQ DLGSGKDYAL KRLLSNEEEK NKAIIQEVCF MKKLSGHPNI VQFCSAASIG 60

KEESDTGQGE FLLLTELCRG QLVEFLKKAE SKGSLSCDTV LKIFYQTCRA VQHMHKQKPP 120

IIHRDLKIEN MLMSNQGTIK LCDFGSATNV AHYPDYNWTA QKRATVEEEI TRNTTPMYRT 180

PEIIDLYSNF PINEKQDIWA LGCILYLLCF RQHPFEDGAK LRIVNGKYSI PQNDTRYTVF 240

HDIIRSALKV NPEERLSITE LVNQL 265

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR001623	; DnaJ_N.
IPR011009	; Kinase-like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF00226	; DnaJ; 1.
PF00069	; Pkinase; 1.
PF10409	; PTEN_C2; 1.

SMARTs

SM00271

; DnaJ; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS50076	; DNAJ_2; 1.
PS51181	; PPASE_TENSIN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013