EKS-ANC-00209

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00209

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF1	410.3	2.7E-123	43	302	260

Status

Unreviewed

Ensembl Protein

ENSACAP00000001303

UniProt Accession

H9G520;

Protein Name

Serine/threonine-protein kinase SBK1

Protein Synonyms/Alias

SH3-binding kinase 1;

Gene Name

SBK1

Gene Synonyms/Alias

SBK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000001406	ENSACAP00000001303	ENSACAT00000001336

Organism

Anolis carolinensis

Functional Description

Protein Length

395

Protein Sequence
(FASTA)

MSAGSIEQEP SRKLACCGVP LITEDMQSLA IRTLSGTDIN KHYDLIRELG KGTYGKVDLV 60

SHKSTGTKMA LKFVNKNKTK LKNFLREFSI TNTLSSSPFI IKVFDVVFET EDCYVFAQEY 120

APGGDLFDII PPQVGLPEDM VKRCVQQLGL ALDYMHSKNL VHRDIKPENV LLFDRDCRRV 180

KLADFGMTRK VGCRVKRISG TIPYTAPEVC QAGRAEGFTV DTSIDVWAFG VLIFCVLTGN 240

FPWEAASASD TFFEEFVRWQ KGRLAGLPSQ WRRFTDNALR MFQRLLALDP EKRCPVKEVF 300

FFIKYDLMSE VRRRPSYRSR KHTGDKLSAG PHRHETPSAC TPTPLKRTIL TEGSMSRLSG 360

SDPGLPSPGS GGRTDGRPDK SKGQMVLATA IEICV 395

Nucleotide Sequence
(FASTA)

ATGAGTGCCG GCTCCATTGA GCAGGAGCCT TCCCGCAAGC TGGCGTGTTG CGGAGTGCCG 60

CTCATCACGG AAGACATGCA GTCGCTGGCC ATCCGCACGC TCTCGGGCAC CGACATCAAC 120

AAGCATTACG ACCTCATCCG CGAGCTGGGG AAAGGGACCT ACGGCAAGGT GGACCTCGTC 180

TCCCACAAGA GCACAGGTAC CAAGATGGCC CTGAAGTTTG TCAACAAGAA TAAGACCAAA 240

CTGAAGAACT TCCTGAGAGA GTTCAGCATT ACCAATACAC TGTCCTCAAG TCCCTTCATC 300

ATCAAGGTCT TTGATGTGGT CTTTGAGACA GAAGACTGCT ATGTCTTTGC CCAGGAATAT 360

GCGCCTGGCG GAGACCTCTT TGACATCATC CCTCCACAGG TGGGACTTCC GGAGGACATG 420

GTGAAGCGCT GTGTGCAGCA GCTGGGCCTG GCACTCGATT ACATGCACAG CAAAAACCTT 480

GTGCACCGGG ACATCAAGCC GGAAAACGTG CTCCTCTTCG ACCGCGACTG TCGGCGGGTC 540

AAGCTGGCCG ATTTCGGCAT GACGCGCAAA GTGGGCTGCC GCGTGAAGCG CATCAGCGGG 600

ACCATCCCGT ACACAGCCCC CGAGGTGTGC CAGGCCGGGC GGGCCGAAGG CTTCACCGTG 660

GACACGAGCA TCGACGTGTG GGCCTTTGGC GTGCTCATCT TCTGCGTGCT GACGGGCAAC 720

TTCCCCTGGG AGGCGGCCTC GGCCTCGGAC ACCTTCTTCG AGGAGTTTGT GCGGTGGCAG 780

AAGGGACGGC TGGCCGGGCT GCCCTCCCAG TGGCGCCGCT TCACGGACAA CGCGCTGCGC 840

ATGTTCCAGC GGCTGCTGGC CCTCGACCCC GAGAAGCGCT GCCCCGTGAA GGAGGTCTTC 900

TTCTTCATCA AGTACGACCT GATGTCGGAG GTCCGCCGCC GGCCCTCCTA CCGCTCCCGC 960

AAGCACACCG GGGACAAGCT CTCCGCGGGG CCCCACCGCC ACGAGACGCC CAGCGCCTGC 1020

ACCCCGACCC CGCTCAAGAG GACCATCCTC ACGGAGGGCA GCATGTCCCG GCTGTCCGGC 1080

TCAGACCCCG GCCTGCCTTC CCCGGGGAGC GGGGGCAGGA CTGACGGGCG GCCGGACAAG 1140

AGCAAAGGCC AAATGGTGCT GGCCACGGCC ATCGAGATCT GCGTCTGA 1188

Domain Profile

S: 1     yelvrklgeGsfgkvlLvehrqsgtkvalKllpkektklkdFlrEfsvglslsshsaivk  60

         y+l+r+lg+G++gkv+Lv+h+ +gtk+alK+++k+ktklk+FlrEfs++++lss+++i+k

Q: 43    YDLIRELGKGTYGKVDLVSHKSTGTKMALKFVNKNKTKLKNFLREFSITNTLSSSPFIIK  102

         99**********************************************************

S: 61    tydvaletadayvFaqEyaplgdLaeaiqekvGlpeaavkrvvaqlasAldflHsrnlvh  120

         ++dv++et+d+yvFaqEyap gdL+++i+++vGlpe++vkr+v+ql+ Ald++Hs+nlvh

Q: 103   VFDVVFETEDCYVFAQEYAPGGDLFDIIPPQVGLPEDMVKRCVQQLGLALDYMHSKNLVH  162

         ************************************************************

S: 121   rdlKpenvLvfdpdcsrvkltDfGltrkkgslvkkkeevipytapelcelvkeeklkvdp  180

         rd+KpenvL+fd+dc+rvkl+DfG+trk+g++vk+ + +ipytape+c++ ++e+++vd+

Q: 163   RDIKPENVLLFDRDCRRVKLADFGMTRKVGCRVKRISGTIPYTAPEVCQAGRAEGFTVDT  222

         ************************************************************

S: 181   svDvWalGvllfvvltgkfPWdkasleadpfyeeflkwqkrklrklPkkfkrlsekalrl  240

         s DvWa+Gvl+f+vltg+fPW++a +++d f+eef++wqk++l  lP++++r++++alr+

Q: 223   SIDVWAFGVLIFCVLTGNFPWEAA-SASDTFFEEFVRWQKGRLAGLPSQWRRFTDNALRM  281

         ************************.999********************************

S: 241   lkklldlepedrskakevakf  261

         +++ll+l+pe+r+++kev+ f

Q: 282   FQRLLALDPEKRCPVKEVFFF  302

         *****************9865

Domain Sequence
(FASTA)

YDLIRELGKG TYGKVDLVSH KSTGTKMALK FVNKNKTKLK NFLREFSITN TLSSSPFIIK 60

VFDVVFETED CYVFAQEYAP GGDLFDIIPP QVGLPEDMVK RCVQQLGLAL DYMHSKNLVH 120

RDIKPENVLL FDRDCRRVKL ADFGMTRKVG CRVKRISGTI PYTAPEVCQA GRAEGFTVDT 180

SIDVWAFGVL IFCVLTGNFP WEAASASDTF FEEFVRWQKG RLAGLPSQWR RFTDNALRMF 240

QRLLALDPEK RCPVKEVFFF 260

Keyword

ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

acs:100566003

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR016234	; Ser/Thr_kinase_Sbk1.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013